Effect of dimethyl sulfoxide (DMSO) on radiation-induced heteroallelic reversion in diploid yeast
| Autor: | D.R. Singh, D. Krishnan, J.M. Mahajan |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
Genotype
biology Chemistry Dimethyl sulfoxide Health Toxicology and Mutagenesis Radical Saccharomyces cerevisiae Reversion Dose-Response Relationship Radiation biology.organism_classification Diploidy Saccharomyces Yeast Scavenger Cold Temperature chemistry.chemical_compound Biochemistry Gamma Rays Mutation Radiolysis Genetics Dimethyl Sulfoxide Molecular Biology Alleles |
| Zdroj: | Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 37:193-199 |
| ISSN: | 0027-5107 |
| Popis: | Dimethyl sulfoxide has cryoprotective and radioprotective properties. It is also an efficient scavenger of radicals produced by radiolysis of water. Gamma-induced reversions of diploid yeast in the presence of this chemical during irradiation have been studied. The dose-modifying factor was in the same range as for survival. When the yeast was irradiated in the frozen state the observed protection by DMSO disappeared. The results are discussed in terms of direct and indirect actions of radiations and the radical-scavenging ability of this chemical. |
| Databáze: | OpenAIRE |
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