Pediatric liver transplantation and COVID-19: a case report
| Autor: | Siavash Gholami, Hamed Nikoupour, Peyman Arasteh, Naghi Dara, Saba Ghazimoghadam, Saman Nikeghbalian, Kourosh Kazemi, Hesameddin Eghlimi |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
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medicine.medical_specialty Pediatrics medicine.medical_treatment Multiple Organ Failure Pneumonia Viral lcsh:Surgery Case Report Liver transplantation Azithromycin Organ transplantation law.invention 03 medical and health sciences 0302 clinical medicine law COVID-19 liver Medicine Humans Pandemics Voriconazole Pediatric Transplantation business.industry COVID-19 Hydroxychloroquine Lopinavir General Medicine lcsh:RD1-811 Intensive care unit Surgery Liver Transplantation Intensive Care Units 030220 oncology & carcinogenesis Child Preschool 030211 gastroenterology & hepatology business Coronavirus Infections medicine.drug |
| Zdroj: | BMC Surgery BMC Surgery, Vol 20, Iss 1, Pp 1-3 (2020) |
| ISSN: | 1471-2482 |
| Popis: | Background Immunosuppressed patients, including individuals with organ transplantation, have been among susceptible groups with regard to COVID-19, on the other hand pediatric patients more commonly undergo a mild clinical course after acquiring COVID-19. To the best of the authors knowledge, to this date very little data exists on COVID-19 in a pediatric patient with liver transplantation. Case presentation We report a three year-old boy who had liver transplantation at 18 months old. He was admitted due to dyspnea with impression of acute respiratory distress syndrome and was then transferred to the intensive care unit. Chest X-ray at admission showed bilateral infiltration. Vancomycin, meropenem, azithromycin, voriconazole and co-trimoxazole were started from the first day of admission. On day 4 of admission, with suspicion of COVID-19, hydroxychloroquine, lopinavir/ritonavir and oseltamivir were added to the antibiotic regimen. PCR was positive for COVID-19. The patient developed multi-organ failure and died on day 6 of admission. Conclusions For pediatric patients with organ transplantations, extreme caution should be taken, to limit and prevent their contact with COVID-19 during the outbreak, as these patients are highly susceptible to severe forms of the disease. |
| Databáze: | OpenAIRE |
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