Cross-sectional Imaging Identifies Flow-mediated Vasodilatation More Accurately Compared with Longitudinal Imaging
| Autor: | Farooq A. Chaudhry, Shrikanth Upadya, Sripal Bangalore, Chandra M. Sehgal, Ajay Shah, Danny Pudpud, Hossein Eftekhari |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
Male medicine.medical_specialty Brachial Artery Sphygmomanometer Sensitivity and Specificity Cross-sectional imaging medicine.artery Image Interpretation Computer-Assisted Humans Medicine Radiology Nuclear Medicine and imaging Brachial artery Aged Ultrasonography Reproducibility Anatomy Cross-Sectional Pixel business.industry Reproducibility of Results Middle Aged Longitudinal imaging Image Enhancement Surgery Vasodilation medicine.anatomical_structure Cuff Female sense organs Cardiology and Cardiovascular Medicine business Nuclear medicine Algorithms Blood Flow Velocity Artery |
| Zdroj: | Journal of the American Society of Echocardiography. 20:1380-1385 |
| ISSN: | 0894-7317 |
| DOI: | 10.1016/j.echo.2007.04.019 |
| Popis: | Objectives: The purpose of this study was to evaluate cross-sectional imaging to longitudinal plane imaging for measurement of flow-mediated dilatation (FMD). Background: Accurate and reproducible assessment of FMD as a measure of endothelial function has important implications. Conventional imaging of the brachial artery is in a longitudinal plane. However, the changes in vasodilatation seen are subtle and minimal (10%-20%) in healthy states with an even smaller change in diseased states, thus, affecting interobserver and intraobserver variability and reproducibility. Methods: Nine healthy volunteers (5 men, 4 women) between the ages of 25 and 65 years had baseline FMD measurements done using both longitudinal and cross-sectional imaging. Brachial artery was occluded by inflating the sphygmomanometer cuff on the arm at a pressure of 150 mm Hg for 5 minutes. The artery was imaged continuously for 5 minutes postdeflation. The images were recorded digitally on a computer and analyzed for area and diameter changes by user-guided semiautomated boundary detection method described by our group earlier. Results: The baseline measurements were normalized to 1.00 for both longitudinal and cross-sectional images. After cuff deflation, the mean longitudinal diameter increased to 1.10 0.04 versus 1.30 0.17 (P .007) for the cross-sectional method. The mean longitudinal measurements were 85.7 13.9 pixels at baseline that increased to 94.3 13.1 pixels for a mean change of 8.6 3.1 pixels after cuff deflation, compared with a mean of 8577.4 2950.8 pixels that increased to 11120.5 3989.4 pixels for a mean change of 2543 1552 pixels by the cross-sectional method (P < .001). Conclusions: Cross-sectional imaging produced a much larger change in area and pixels compared with longitudinal imaging. This translates into greater sensitivity in detecting small changes produced by FMD. (J Am Soc Echocardiogr 2007;20: 1380-1385.) |
| Databáze: | OpenAIRE |
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