Serologic evidence of exposure to Rift Valley fever virus detected in Tunisia
| Autor: | Elyes Zhioua, Stuart D. Dowall, Andrew Bosworth, Anitha Varghese, Roger Hewson, Wasfi Fares, Amel Letaief, Hanene Tiouiri, Abir Znazen, T. Ghabbari, M. Ben Jemaa, M. Chakroun |
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| Přispěvatelé: | Laboratory of Vector Ecology, Institut Pasteur de Tunis, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), SAROST SA [Tunis, Tunisie], Service de Médecine Interne et Maladies Infectieuses, CHU F. Hached |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Veterinary medicine
Tunisia 040301 veterinary sciences 030231 tropical medicine Population Microbiology Arbovirus Virus Immunoglobulin G Serology lcsh:Infectious and parasitic diseases 0403 veterinary science 03 medical and health sciences 0302 clinical medicine vectors Medicine Seroprevalence lcsh:RC109-216 education ComputingMilieux_MISCELLANEOUS education.field_of_study biology seroprevalence business.industry Outbreak 04 agricultural and veterinary sciences medicine.disease Virology 3. Good health Infectious Diseases Immunoglobulin M unexplained acute fever biology.protein Original Article business [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology |
| Zdroj: | New Microbes and New Infections New Microbes and New Infections, Wiley Online Library 2016, 9, pp.1--7. ⟨10.1016/j.nmni.2015.10.010⟩ New Microbes and New Infections, Vol 9, Iss C, Pp 1-7 (2016) |
| ISSN: | 2052-2975 |
| DOI: | 10.1016/j.nmni.2015.10.010⟩ |
| Popis: | Rift Valley fever virus (RVFv) is capable of causing dramatic outbreaks amongst economically important animal species and is capable of causing severe symptoms and mortality in humans. RVFv is known to circulate widely throughout East Africa; serologic evidence of exposure has also been found in some northern African countries, including Mauritania. This study aimed to ascertain whether RVFv is circulating in regions beyond its known geographic range. Samples from febrile patients (n=181) and nonfebrile healthy agricultural and slaughterhouse workers (n=38) were collected during the summer of 2014 and surveyed for exposure to RVFv by both serologic tests and PCR. Of the 219 samples tested, 7.8% of nonfebrile participants showed immunoglobulin G reactivity to RVFv nucleoprotein and 8.3% of febrile patients showed immunoglobulin M reactivity, with the latter samples indicating recent exposure to the virus. Our results suggest an active circulation of RVFv and evidence of human exposure in the population of Tunisia. |
| Databáze: | OpenAIRE |
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