A carbon nanomaterial derived from a nanoscale covalent organic framework for photothermal therapy in the NIR-II biowindow

Autor:	Le-Le Zhou, Qun Guan, Li-Na Zhou, Meng-Di Li, Yan-An Li, Yu-Bin Dong, Guo-Xin Qin, Wen-Yan Li
Rok vydání:	2020
Předmět:	Materials science Photothermal Therapy Nanoparticle chemistry.chemical_element Nanotechnology 02 engineering and technology 010402 general chemistry 01 natural sciences Theranostic Nanomedicine Catalysis Mice Microscopy Electron Transmission Materials Chemistry Animals Humans Irradiation Nanoscopic scale Metal-Organic Frameworks Spectroscopy Near-Infrared Metals and Alloys General Chemistry Microporous material Photothermal therapy 021001 nanoscience & nanotechnology Xenograft Model Antitumor Assays Carbon Nanostructures 0104 chemical sciences Surfaces Coatings and Films Electronic Optical and Magnetic Materials chemistry MCF-7 Cells Microscopy Electron Scanning Ceramics and Composites 0210 nano-technology Porosity Pyrolysis Powder Diffraction Covalent organic framework
Zdroj:	Chemical Communications. 56:7793-7796
ISSN:	1364-548X 1359-7345
DOI:	10.1039/d0cc00861c
Popis:	Herein, we report a microporous carbon nanomaterial that was generated from a nanoscale covalent organic framework precursor via a simple pyrolysis approach. The obtained carbon-based nanoparticles possessed a broad NIR absorption capacity and exhibited a high level of photothermal conversion ability (η = 50.6%) in the NIR-II biowindow. Its excellent PTT antitumor efficiency was fully evidenced by in vitro and in vivo experiments under 1064 nm laser irradiation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc0f5582b96883775990d79621b08746 https://doi.org/10.1039/d0cc00861c Zobrazit plný text záznamu