Cross-linking-induced permanently perpendicular helix orientation in surface-grafted polyglutamate films
| Autor: | E.J. Vorenkamp, Jeroen Luijten, Gerard W. Nijboer, Daan Y. Groeneveld, Arend Jan Schouten |
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| Přispěvatelé: | Polymers at Surfaces and Interfaces |
| Jazyk: | angličtina |
| Rok vydání: | 2007 |
| Předmět: |
L-GLUTAMATE
(3-AMINOPROPYL)TRIETHOXYSILANE Materials science Silicon chemistry.chemical_element Methacrylate chemistry.chemical_compound Monolayer Polymer chemistry Electrochemistry Perpendicular General Materials Science AMINO-ACIDS N-CARBOXYANHYDRIDES Spectroscopy (3-Aminopropyl)triethoxysilane Polyglutamate THIN-LAYERS POLYPEPTIDES DERIVATIVES Substrate (chemistry) MONOLAYERS Surfaces and Interfaces Condensed Matter Physics chemistry Helix GAMMA-BENZYL BEHAVIOR |
| Zdroj: | Langmuir, 23(15), 8163-8169. AMER CHEMICAL SOC |
| ISSN: | 0743-7463 |
| Popis: | Using a chemical cross-linking procedure, surface-grafted polyglutamate films with a permanently perpendicular helix orientation were prepared. A surface-grafted alpha-helical polyglutamate film containing polymerizable side groups was synthesized by ring-opening terpolymerization of 50 molar% gamma-methyl-L-glutamate N-carboxyanhydride (NCA), 30% gamma-stearyl-L-glutamate NCA and 20% gamma-4-vinylbenzyl-L-glutamate NCA initiated from a silicon substrate functionalized with primary amino groups. The average tilt angle of the end-grafted helices in this film is approximately 66 degrees, indicating a nearly parallel helix orientation with respect to the substrate surface. After swelling of the grafted terpolyglutamate film in stearyl methacrylate and subsequent radical cross-linking, the average helix tilt angle decreases to about 11 degrees, indicating an almost perpendicular helix orientation. The film thickness increases accordingly from 151 A before to approximately 390 A after cross-linking. Extensive solvent treatment of the cross-linked film shows that the perpendicular helix orientation is permanent. |
| Databáze: | OpenAIRE |
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