Fulminant Herpes Simplex Hepatitis Secondary to Adalimumab in Crohn’s Disease: A Case Report
| Autor: | Anna Balog, Jan F. Silverman, Mark Bunker, Kanika Goel |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Crohn’s disease
medicine.medical_specialty Fulminant viruses Azathioprine Case Report medicine.disease_cause Inflammatory bowel disease Gastroenterology 03 medical and health sciences 0302 clinical medicine Fulminant hepatic failure inflammatory bowel disease Internal medicine adalimumab medicine Adalimumab hepatitis Hepatitis lcsh:R5-920 Crohn's disease business.industry TNF-α inhibitor General Medicine medicine.disease herpes simplex virus digestive system diseases Herpes simplex virus 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology lcsh:Medicine (General) business medicine.drug |
| Zdroj: | Clinical Medicine Insights. Case Reports Clinical Medicine Insights: Case Reports, Vol 12 (2019) |
| ISSN: | 1179-5476 |
| Popis: | Herpes simplex virus (HSV) hepatitis is an uncommon cause of fulminant hepatic failure, seen mostly in immunocompromised patients. Conventional treatment modalities for inflammatory bowel disease (IBD), such as steroids and azathioprine, have been known to cause HSV hepatitis. However, the reported incidence of HSV hepatitis in IBD patients undergoing tumor necrosis factor (TNF)-α inhibitor therapy is very rare. In this case report, we describe a rare case of fulminant HSV hepatitis that developed in a patient with Crohn’s disease after treatment with the TNF-α inhibitor, adalimumab. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|