The comparison of dexmedetomidine and midazolam used for sedation of patients during upper endoscopy: A prospective, randomized study
| Autor: | Yusuf Akcan, Ilknur Suidiye Yorulmaz, Yavuz Demiraran, Esin Korkut, Buket Kocaman, Ali Tamer, Gülbin Sezen |
|---|---|
| Přispěvatelé: | BAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, BAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Demiraran, Yavuz, Korkut, Esin, Tamer, Ali, Yorulmaz, İlknur, Kocaman, Buket, Sezen, Gülbin, Akcan, Yusuf |
| Jazyk: | angličtina |
| Rok vydání: | 2007 |
| Předmět: |
Adult
Male medicine.medical_specialty Respiratory rate Visual analogue scale medicine.drug_class Sedation Midazolam Conscious Sedation Heart Rate Heart rate Humans Hypnotics and Sedatives Medicine Retching Endoscopy Digestive System Prospective Studies Dexmedetomidine lcsh:RC799-869 business.industry Gastroenterology Endoscopy General Medicine Surgery Sedative Anesthesia Original Article Female lcsh:Diseases of the digestive system. Gastroenterology medicine.symptom business Anesthetics Intravenous medicine.drug |
| Zdroj: | Canadian Journal of Gastroenterology, Vol 21, Iss 1, Pp 25-29 (2007) |
| Popis: | WOS:000243835300004 PubMed: 17225879 The aim of the present prospective, randomized study was to investigate and compare the safety and efficacy of dexmedetomidine versus midazolam in providing sedation for gastroscopy. A total of 50 adult patients (25 patients receiving dexmedetomidine and 25 patients receiving midazolam), 18 to 60 years of age, and rated I and II on the American Society of Anesthesiologists physical status classification system were included. A brief questionnaire was used to collect demographic data; patients were asked to rate anxiety, satisfaction wit care to data and expected discomfort on a visual analogue scale. The following parameters were measured continuously and recorded every minute; heart rate, mean arterial pressure, hemoglobin oxygen saturation and respiratory rate. The two groups were similar with regard to age, body mass index, sex, education, duration of endoscopy, and ethanol or tobacco use. After the procedure, full recovery time, mean arterial pressure, heart rate, respiratory rate and hemoglobin oxygen saturation levels were similar in both groups. Both groups also had low levels of perceived procedural gagging, discomfort and anxiety scores (P > 0.05), and high satisfaction levels (90.1+/-3.0 for dexmedetomidine versus 84.9+/-4.5 for midazolam; P>0.05). Retching and endoscopist satisfaction were significantly different in patient receiving dexmedetomidine versus those receiving midazolam (88.8+/-6.5 versus 73.5+/-16.4, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|