Most infectious complications in parenterally fed trauma patients are not due to elevated blood glucose levels
| Autor: | M. Keith Hanna, Anne Laulederkind, Kenneth A. Kudsk |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Blood Glucose
medicine.medical_specialty Parenteral Nutrition 030309 nutrition & dietetics Medicine (miscellaneous) Infections Enteral administration Gastroenterology 03 medical and health sciences Route of administration 0302 clinical medicine Enteral Nutrition Intensive care Internal medicine Statistical significance Sepsis medicine Humans Risk factor Prospective cohort study Randomized Controlled Trials as Topic Retrospective Studies 0303 health sciences Nutrition and Dietetics business.industry Incidence Length of Stay Surgery Parenteral nutrition Hyperglycemia Wound Infection Wounds and Injuries 030211 gastroenterology & hepatology Complication business |
| Zdroj: | JPEN. Journal of parenteral and enteral nutrition. 25(4) |
| ISSN: | 0148-6071 |
| Popis: | To determine the relationship between hyperglycemia and infectious complications in nutritional studies of trauma patients.Retrospective review of serum glucose values in two published randomized, prospective studies of patients receiving either enteral or parenteral feeding (trial 1) or isonitrogenous, isocaloric enteral diets (trial 2). Trial 2 also included patients prospectively followed who received little or no enteral feeding.Patients randomized to enteral or parenteral feeding in trial 1 exhibited no significant differences in the highest recorded serum glucose (SG) until the fourth or fifth day after protocol entry. SG tended to be higher in infected than non-infected patients in the first 4 hospital days, but SG was far below values considered to increase the risk for infection (SG220 mg/dL). In trial 2, glucose levels tended to be slightly higher in infected than in noninfected patients within the first 5 days reaching statistical significance by day 5. Unfed control patients had similar SG values but significantly more major infectious complications.Patients developing infections had slightly higher SG levels than noninfected patients early in admission, but these SG values were far below levels considered a risk for infective complications. Significant hyperglycemia does not explain differences in infectious complications in critically ill trauma patients randomized to various routes and types of nutrition. |
| Databáze: | OpenAIRE |
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