A REVIEW OF ANALYTICAL MODELS OF STRAY RADIATION EXPOSURES FROM PHOTON- AND PROTON-BEAM RADIOTHERAPIES
| Autor: | Wayne D. Newhauser, William P Donahue, Lydia J. Wilson, Christopher W. Schneider, Suman Shrestha |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Risk
medicine.medical_specialty Photon Neoplasms Radiation-Induced medicine.medical_treatment 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Radiation Protection medicine Proton Therapy Humans Scattering Radiation Radiology Nuclear Medicine and imaging Medical physics Proton therapy Neutrons Photons Radiation Radiological and Ultrasound Technology Phantoms Imaging Radiotherapy Planning Computer-Assisted Public Health Environmental and Occupational Health Second cancer Cancer survival Radiotherapy Dosage General Medicine Stray radiation Radiation Exposure Clinical Practice Radiation therapy 030220 oncology & carcinogenesis Photon therapy Radiotherapy Intensity-Modulated Monte Carlo Method Algorithms Software |
| Zdroj: | Radiation protection dosimetry. 180(1-4) |
| ISSN: | 1742-3406 |
| Popis: | External-beam radiation therapy is safe, effective and widely used to treat cancer. With 5-year cancer survival for adults above 70%, increasingly research is focusing on quantifying and reducing treatment-related morbidity. Reducing exposures to healthy tissues is one strategy, which can be accomplished with advanced-technology radiotherapies, such as intensity-modulated photon therapy and proton therapy. Both of these modalities provide good conformation of the therapeutic dose to the tumor volume, but they also deliver stray radiation to the whole body that increases the risk of radiogenic second cancers. To minimize these risks, one needs to create and compare candidate treatment plans that explicitly take into account these risks. Currently, clinical practice does not include routine calculation of stray radiation exposure and, consequently, the assessment of corresponding risks is difficult. In this article, we review recent progress toward stray dose algorithms that are suitable for large-scale clinical use. In particular, we emphasize the current state of physics-based dose algorithms for intensity-modulated photon radiotherapy and proton therapy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|