Absolute protein quantification of clinically relevant metabolizing enzymes by mass spectrometry-based targeted proteomics
| Autor: | Busch, D, Gröer, C, Drozdzik, M, Siegmund, W, Oswald, S |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | 16. Jahreskongress für Klinische Pharmakologie; 20141009-20141010; Köln; DOC14vklipha30 /20140925/ |
| DOI: | 10.3205/14vklipha30 |
| Popis: | Aim: The pharmacokinetics of many drugs is markedly influenced by intestinal and hepatic biotransformation enzymes such as cytochrome P450 (CYP450) enzymes and UDP-glucuronosyltransferases (UGT). In order to predict their impact on drug disposition as well as on drug-drug interactions, data on their[for full text, please go to the a.m. URL] 16. Jahreskongress für Klinische Pharmakologie |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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