Bi-Langmuir Isotherms' Applicability for Description of Interaction of Ion-Exchange Sorbents with Protein Mixtures

Autor: A. T. Melenevsky, A. A. Demin
Rok vydání: 2006
Předmět:
Zdroj: Journal of Chromatographic Science. 44:181-186
ISSN: 1945-239X
0021-9665
DOI: 10.1093/chromsci/44.4.181
Popis: The sorption of a protein pair on carboxylic cation exchangers with various contents of ionogenic groups is examined. The bi-Langmuir isotherm calculation is carried out from sorption data for single-component systems. It is shown that good agreement of calculated and experimental data is reached only when protein-sorbent interaction weakens because of implementation of the competitive sorption mechanism.
Databáze: OpenAIRE