Tl(+) induces both cationic and transition pore permeability in the inner membrane of rat heart mitochondria
| Autor: | Sergey M. Korotkov, Artemy V. Novozhilov, V. P. Nesterov, Irina V. Brailovskaya, V. V. Furaev |
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| Rok vydání: | 2013 |
| Předmět: |
Male
Cell Membrane Permeability Physiology Cell Respiration Biology Mitochondrion Mitochondria Heart chemistry.chemical_compound Oxygen Consumption Diazoxide medicine Myocyte Inner membrane Animals Rats Wistar Thallium Membrane Potential Mitochondrial MPTP Cell Biology Cations Monovalent Rats Disease Models Animal chemistry Mitochondrial permeability transition pore Biochemistry Permeability (electromagnetism) Pinacidil Mitochondrial Membranes Biophysics medicine.drug |
| Zdroj: | Journal of bioenergetics and biomembranes. 45(6) |
| ISSN: | 1573-6881 |
| Popis: | Effects of Tl + were studied in experiments with iso- lated rat heart mitochondria (RHM) injected into 400 mOsm medium containing TlNO3 and a nitrate salt (KNO3 or NH4NO3 )o r TlNO3 and sucrose. Tl + increased permeability of the inner membrane of the RHM to K + and H + . This manifested as an increase of the non-energized RHM swelling, in the order of sucrose < K + |
| Databáze: | OpenAIRE |
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