Further evidence of an Amerindian contribution to the Polynesian gene pool on Easter Island
| Autor: | Erik Thorsby, B. Woldseth, Siri Tennebø Flåm, Alicia Sanchez-Mazas, B. M. Dupuy, Marcelo Fernandez-Vina |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Mitochondrial DNA Immunology Population Polynesian Human leukocyte antigen HLA-C Antigens Biology Human leukocyte antigen alleles Y chromosome Biochemistry HLA-DQ alpha-Chains Polynesia 03 medical and health sciences 0302 clinical medicine Amerindian Gene Frequency HLA Antigens HLA-DQ Antigens Y chromosomes Genetics HLA-B Antigens Immunology and Allergy Humans Allele education 030304 developmental biology ddc:599.9 Aged Aged 80 and over 0303 health sciences education.field_of_study HLA-A Antigens Indians South American Haplotype General Medicine Easter Island Gene Pool HLA-DR Antigens Middle Aged Genetics Population Haplotypes Evolutionary biology Gene pool 030215 immunology HLA-DRB1 Chains |
| Zdroj: | Tissue antigens Tissue Antigens, Vol. 73, No 6 (2009) pp. 582-585 |
| ISSN: | 0001-2815 |
| DOI: | 10.1111/j.1399-0039.2009.01233.x |
| Popis: | Available evidence suggests a Polynesian origin of the Easter Island population. We recently found that some native Easter Islanders also carried some common American Indian (Amerindian) human leukocyte antigen (HLA) alleles, which probably were introduced before Europeans discovered the island in 1722. In this study, we report molecular genetic investigations of 21 other selected native Easter Islanders. Analysis of mitochondrial DNA and Y chromosome markers showed no traces of an Amerindian contribution. However, high-resolution genomic HLA typing showed that two individuals carried some other common Amerindian HLA alleles, different from those found in our previous investigations. The new data support our previous evidence of an Amerindian contribution to the gene pool on Easter Island. |
| Databáze: | OpenAIRE |
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