[Drug prescription in Italian Residential Facilities]
| Autor: | Gruppo Nazionale Progres, Silva Fava, Domenico Semisa, Rodolfo Tomasi, Rocco Micciolo, Giovanni de Girolamo, Giovanni Santone, Angelo Picardi |
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| Rok vydání: | 2005 |
| Předmět: |
Adult
Male medicine.medical_specialty genetic structures Adolescent medicine.medical_treatment Sample (statistics) Tardive dyskinesia Drug Prescriptions Residential Facilities medicine Humans Medical prescription Adverse effect Antipsychotic Aged Polypharmacy Psychotropic Drugs business.industry Mental Disorders Public Health Environmental and Occupational Health Middle Aged medicine.disease Psychiatry and Mental health Psychotropic drug Italy Family medicine Structured interview Female business |
| Zdroj: | Epidemiologia e psichiatria sociale. 14(2) |
| ISSN: | 1121-189X |
| Popis: | SUMMARYAims— To investigate in a representative national sample (N=2,962) of patients living in Residential Facilities (RFs) patterns of polypharmacy as well as related variables, association between diagnoses and therapeutic patterns, and the rate of adverse events.Methods— Structured interviews focusing on each patient were conducted by trained research assistants with the manager and staff of each RF. Patients were rated with the HoNOS and the SOFAS, and comprehensive information about their sociodemographic and clinical status, and their pharmacological regimes were collected.Results— Conventional antipsychotics and second-generation antipsychotics were prescribed to 65% and 43% of the sample, respectively. Benzodiazepines were prescribed to two-thirds of the sample, while antidepressants were the least-used class of psychotropics. Polypharmacy was common: on average, each treated patient was taking 2.7 drugs (±1.1); antipsychotic polypharmacy was also common. Many prescriptions were loosely related to specific diagnoses. Antiparkinsonianian drugs were prescribed to approximately 1/4 of the sample. Mild or severe adverse events in the previous month were reported for 9.9% and 1.4% of the sample, respectively. About 15% of patients suffered from tardive dyskinesia.Conclusions— Psychotropic drug prescription patterns for severe patients living in RFs are only sometimes satisfactory and offer the opportunity of improvement. Specific actions are required to improve prescription patterns for severe patients in RFs.Declaration of Interest: in the past two years GdG has received two speaker fees from Janssen-Cilag and from Eli Lilly; GS has received one speaker fee from Solvay. RM, AP, SF and RT have received no fees or other financial support from pharmaceutical companies. |
| Databáze: | OpenAIRE |
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