Effect of plant sterols from rice bran oil and triterpene alcohols from sheanut oil on serum lipoprotein concentrations in humans
| Autor: | Gert W Meijer, Martijn B. Katan, M.N. Vissers, Peter L. Zock |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2000 |
| Předmět: |
Male
4 4'-dimethylsterols Triterpene alcohols Medicine (miscellaneous) chemistry.chemical_compound Triterpene 4'-dimethylsterols Food science Human Nutrition & Health chemistry.chemical_classification Nutrition and Dietetics Cross-Over Studies Humane Voeding & Gezondheid Rice bran oil food and beverages Phytosterols Middle Aged Serum cholesterol 4-desmethylsterols Cholesterol Biochemistry lipids (amino acids peptides and proteins) Female Adult food.ingredient Adolescent Lipoproteins Sitosterols Biology Plant sterols food Double-Blind Method Plant Oils Humans VLAG Analysis of Variance Sunflower oil Margarine Sterol Triterpenes Sheanut oil Diet chemistry Unsaponifiable Blood chemistry β-sitosterol |
| Zdroj: | American Journal of Clinical Nutrition, 72, 1510-1515 American Journal of Clinical Nutrition 72 (2000) |
| ISSN: | 0002-9165 |
| Popis: | Background Intake of unsaponifiable compounds from edible oils, such as plant sterols, can lower serum cholesterol concentrations in humans. However, little is known about effects of other chemically related unsaponifiables in edible oils, such as triterpene alcohols. Objective We studied the effects of plant sterols from rice bran oil and triterpene alcohols from sheanut oil on cholesterol concentrations in healthy, normolipemic volunteers. Design Twenty-eight men and 32 women consumed 29 g/d of 3 margarines for 3 wk each on a crossover, double-blind basis. A margarine based on sunflower oil was used as the control. Concentrates of plant sterols from rice bran oil or triterpene alcohols from sheanut oil were added to make 2 experimental margarines with the same fatty acid composition as the control margarine. Results Intake of 2.1 g plant sterols/d from rice bran oil decreased total cholesterol by 0.19 mmol/L (95% CI: -0.31, -0.07 mmol/L) and LDL cholesterol by 0.20 mmol/L (95% CI: -0.30, -0.10 mmol/L). HDL-cholesterol and triacylglycerol concentrations did not change significantly. Intake of 2.6 g triterpene alcohols/d from sheanut oil did not significantly affect lipoprotein concentrations in all subjects combined. Conclusions We found that 2.1 g plant sterols/d from rice bran oil lowered serum total cholesterol by 5% and LDL cholesterol by 9% in normolipemic humans, whereas triterpene alcohols from sheanut oil did not significantly affect lipoprotein concentrations in all subjects combined. The effect of rice bran oil sterols is probably due to ss-sitosterol and other 4-desmethylsterols and not to 4,4'-dimethylsterols. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|