Oxidative rearrangement of alkenes using in situ generated hypervalent iodine(III)

Autor:	Nazli Jalalian, Anees Ahmad, Paulo Scarassati, Berit Olofsson, Luiz F. Silva
Rok vydání:	2013
Předmět:	In situ Organisk kemi Organic Chemistry Hypervalent molecule chemistry.chemical_element Rearrangement Oxidative phosphorylation Alkenes Photochemistry Iodine Biochemistry chemistry SÍNTESE ORGÂNICA Oxidation Drug Discovery Organic chemistry Ring contraction Hypervalent iodine
Zdroj:	Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2013.08.012
Popis:	A novel protocol for the oxidative rearrangement of alkenes using in situ generated hypervalent iodine(III) was developed. This approach uses inexpensive, readily available, and stable chemicals (PhI, mCPBA, and TsOH) giving rearrangement products in yields comparable to those obtained using the more expensive commercially available [hydroxy(tosyloxy)iodo]benzene [HTIB or Koser's reagent]. Additionally, an alternative protocol for the synthesis of 1-methyl-2-tetralone through the one-step epoxidation/rearrangement of 4-methyl-1,2-dihydronaphthalene using mCPBA and TsOH was developed. AuthorCount:5
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe89316134c67d4829871eabbde9cb6 Zobrazit plný text záznamu Full Text from ScienceDirect