The prevalence and spectrum of mucocutaneous disease in South African people living with HIV and accessing care at a district-level hospital

Autor:	Karis Moxley, Johann de Wet, Susanna M H Kannenberg, Saskya Claasens, Rhodine Smith, Henry F Jordaan, Willem I Visser
Rok vydání:	2020
Předmět:	Pediatrics medicine.medical_specialty mucocutaneous disease Mucocutaneous zone Ethnic group Disease 030207 dermatology & venereal diseases 03 medical and health sciences South Africa 0302 clinical medicine Seborrheic dermatitis Medicine 030212 general & internal medicine Prospective cohort study Original Research business.industry district-level hospitals lcsh:Public aspects of medicine HIV lcsh:RA1-1270 medicine.disease Confidence interval Infectious Diseases ART Tinea capitis business Viral load
Zdroj:	Southern African Journal of HIV Medicine Southern African Journal of HIV Medicine, Vol 21, Iss 1, Pp e1-e7 (2020) Southern African Journal of HIV Medicine; Vol. 21 No. 1 (2020) Southern African Journal of HIV Medicine, Volume: 21, Issue: 1, Pages: 1-7, Published: 2020
ISSN:	2078-6751 1608-9693
Popis:	Background: Although the association between human immunodeficiency virus (HIV) and mucocutaneous diseases has been well studied within South African specialist centres, there is limited data from district-level hospitals. Available data may, therefore, fail to reflect the prevalence and full spectrum of dermatoses seen in people living with HIV (PLWH). Objectives: To determine the prevalence and spectrum of dermatoses seen in PLWH. Method: We conducted a cross-sectional, descriptive study of 970 PLWH (men and women, ≥ 18 years old) accessing care at Karl Bremer Hospital, a district-level hospital located in the Western Cape province, South Africa, between 01 September 2016 and 28 February 2017. Results: The prevalence of mucocutaneous disease in this sample was 12.7% (95% confidence interval [CI] 0.11–0.15). Non-infectious dermatoses comprised 71.0% of the disorders. Pruritic papular eruption (20.0%) and seborrheic dermatitis (6.0%) were the most common non-infectious dermatoses. Tinea corporis (8.0%) and oral candidiasis (6.0%) were the most prevalent infectious dermatoses. There was no significant association between skin disease category (infectious or non-infectious dermatoses) and patient demographics (gender and ethnicity) or HIV-disease characteristics (CD4+ cell count, viral load and duration of antiretroviral therapy [ART]). Conclusion: This study provides valuable scientific data on the prevalence and spectrum of mucocutaneous disease in PLWH attending a South African district-level hospital. Prospective studies conducted in other district-level centres across the country are required to determine the lifetime prevalence and spectrum of dermatoses in PLWH in the ART era.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe602df74f32b5a5e8c0386e0d1c6db https://pubmed.ncbi.nlm.nih.gov/33354365 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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