Experimental Infection of Pigs with a Parvovirus Isolated from the Diarrheic Feces of a Pig
| Autor: | Akihiro Izumida, Hisao Yasuhara, Morimasa Yamanaka, Yuji Inaba, Masahisa Nakai, Tadashi Hirahara |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Diarrhea
Aging Swine Hysterectomy Virus Parvoviridae Infections Parvovirus Feces Pregnancy medicine Animals Seroconversion Swine Diseases Infectivity General Veterinary biology Inoculation biology.organism_classification Virology Animals Suckling Animals Newborn Nasal Swab Female medicine.symptom Digestive System |
| Zdroj: | Journal of Veterinary Medical Science. 57:629-634 |
| ISSN: | 1347-7439 0916-7250 |
| DOI: | 10.1292/jvms.57.629 |
| Popis: | A parvovirus (the H-45 strain) isolated from an outbreak of epizootic diarrhea in swine was examined to observe the infectivity and pathogenecity in swine. The virus infection by intranasal route was demonstrated in each group of 2- and 5-day-old colostrum-deprived pigs, 30- and 100-day-old pigs by virus recovery from the nasal and rectal swabs, and detecting seroconversion. The virus was recovered from rectal swabs up to 14 days after inoculation and from nasal swabs up to 9 days. Uninoculated pigs were infected with the virus by contacting with the inoculated pigs. Between 1 and 5 days after inoculation, the inoculated pigs of 2, 5 and 30 days old developed diarrhea and then all the pigs of 2 days old died, resulting from dehydration. In the pigs died after intranasal inoculation, the virus was recovered mainly from the respiratory and gastrointestinal tracts. One hundred-day-old pigs showed no clinical signs. The pathological change was characterised by congestion and edema with hemorrhage in the epithelium of the small intestines exhibiting additional degeneration and desquamation of the epithelial cells. |
| Databáze: | OpenAIRE |
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