Patients with bipolar disorders share similar but attenuated prospective memory impairments with patients with schizophrenia
| Autor: | Raymond C.K. Chan, Simon S.Y. Lui, William W.H. Chui, Amy C. Y. Liu, David Shum, Eric F.C. Cheung, Ya Wang |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male Analysis of covariance Memory Disorders Bipolar Disorder Intelligence quotient Memory Episodic Repeated measures design Comorbidity medicine.disease Young Adult Psychiatry and Mental health Retrospective memory Schizophrenia Prospective memory medicine Humans Female Bipolar disorder Psychology Neurocognitive Applied Psychology Clinical psychology |
| Zdroj: | Psychological Medicine. 43:1639-1649 |
| ISSN: | 1469-8978 0033-2917 |
| DOI: | 10.1017/s003329171200236x |
| Popis: | BackgroundProspective memory (PM) refers to the ability to remember to carry out an intended action in the future. PM is consistently found to be impaired in individuals with schizophrenia. Bipolar disorder and schizophrenia may represent conditions along a continuum, and share similar neurocognitive and genetic architecture. This study aimed to compare the nature and extent of PM impairment in individuals with schizophrenia and bipolar disorder.MethodParticipants were 38 out-patients with schizophrenia and 40 out-patients with bipolar disorder in an early psychosis intervention programme, and 37 healthy controls. Time-, event- and activity-based PMs were assessed using a dual-task laboratory paradigm. Self-reported PM performance was gauged using the Prospective and Retrospective Memory Questionnaire. Analysis of covariance (ANCOVA), with intelligence quotient (IQ) and education included as covariates, was used to examine group difference on various types of PM. Repeated measures of ANCOVA were used to examine the group × PM type interaction effect. Correspondence between laboratory and self-reported PM measures was examined using correlational analysis.ResultsThe group × PM type interaction effect was not significant, but the main effect of group was significant. Patients with schizophrenia and patients with bipolar disorder both performed more poorly than healthy participants in PM. The two clinical groups did not significantly differ in PM. Laboratory and self-reported PM measures did not correlate significantly with each other.ConclusionsPatients with bipolar disorder shared a similar PM impairment with those with schizophrenia. Findings of this study extended the similarity in neurocognitive impairments between the two psychiatric disorders to PM. |
| Databáze: | OpenAIRE |
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