Serum Sp-D Levels as a Biomarker of Lung Injury in Children Suffering of Bronchopneumonia
| Autor: | Nahla A Bahgat Abd-Ellatif, Amira A Abd El-Rahman Mosbah, Ehab Ibrahim Sorour, Mohamed Fawzy M Awadallah |
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| Rok vydání: | 2012 |
| Předmět: |
Male
medicine.medical_specialty business.industry Bronchopneumonia Lung injury Pulmonary Surfactant-Associated Protein D medicine.disease Gastroenterology Surgery Icu admission Child Preschool Internal medicine Baseline characteristics Healthy control medicine Humans Biomarker (medicine) Asthmatic patient Female Stage (cooking) business Lung Biomarkers |
| Zdroj: | Journal of the Egyptian Society of Parasitology. 42:25-32 |
| ISSN: | 1110-0583 |
| Popis: | The efficacy of SP-D concentration as a useful biomarker of the severity of lung injury in children with bronchopneumonia with or without chronic airway disease was studied. A total of 48 patients (2 to 4 years old) diagnosed bronchopneumonia were admitted to Department of Pediatrics, Al-Dar hospital, Al-Madinah, Saudi Arabia over the year 2009. They were divided into two groups: G1 included patients without any underlying disease and G2 included asthmatic patients. They were assigned to one of three categories. Stage A patients without oxygen dosage, Stage B patients required oxygen dosage, and Stage C patients required ICU admission. We evaluated baseline characteristics, clinical features, and serum SP-D concentration in G1, G2, and G3a (healthy control cross-matched infants). The mean serum SP-D concentrations in G1 and G2 were higher than those in G3 (118.7 +/- 46.2 & 39.7 +/- 18.7 ng/ml, respectively), but also higher in G2 than in G1 (149.9 +/- 52.8 & 109.8 + 36.7 ng/ml, respectively). The mean serum SP-D concentrations were higher in Stage C than in Stages A or B patients, and mean serum SP-D concentrations were higher in Stage B than in Stage A. |
| Databáze: | OpenAIRE |
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