Contribution of right ventricular dysfunction to heart failure mortality: a meta-analysis
| Autor: | Carmen Garrote, Julia Martín, David Alonso, Miguel Angel Rodríguez, Cristina Olalla-Gómez, Ignacio Iglesias-Garriz, María López-Benito |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
medicine.medical_specialty
Funnel plot Ventricular Dysfunction Right Risk Assessment Ventricular Function Left Ventricular Dysfunction Left Patient Admission Risk Factors Internal medicine medicine Odds Ratio Humans Heart Failure Chi-Square Distribution business.industry General Medicine Publication bias Odds ratio medicine.disease Prognosis Right ventricular dysfunction Meta-analysis Heart failure Cardiology Ventricular Function Right Cardiology and Cardiovascular Medicine Risk assessment business Chi-squared distribution |
| Zdroj: | Reviews in cardiovascular medicine. 13(2-3) |
| ISSN: | 1530-6550 |
| Popis: | Right ventricular systolic dysfunction (RVSD) has been related to prognosis in patients with heart failure (HF) and/or left ventricular systolic dysfunction. However, most of the studies addressing this issue are not large enough, have different inclusion criteria, and use different methods to evaluate RV function to draw definite conclusions. We sought to investigate the association between RVSD and outcomes in patients with left ventricular dysfunction. Eleven studies of 40 (27.5%), with 4732 patients, were included in the meta-analysis. RVSD was present in 2234 patients (47.2%). Four of the studies had admission for HF as an endpoint. We found a significant association between RVSD and overall mortality with significant between-studies heterogeneity and presence of publication bias (funnel plot). A significant association was found between RVSD and admission for HF. RVSD is associated with overall mortality and admission for HF during follow-up. Significant between-studies heterogeneity and publication bias must be taken into account when interpreting this information. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|