Antioxidative Flavonol Glucuronides and Anti-HBsAg Flavonol from Rotala rotundifolia
| Autor: | Sheau-Farn Yeh, Li-Jie Zhang, Yao-Haur Kuo, Ya-Ten Yu, Li-Ming Yang Kuo |
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| Rok vydání: | 2011 |
| Předmět: |
chemistry.chemical_classification
HBsAg Chromatography biology Superoxide DPPH lcsh:R Flavonoid lcsh:Medicine biology.organism_classification Rotala rotundifolia chemistry.chemical_compound Flavonol glucuronides Complementary and alternative medicine chemistry Biochemistry Anti-oxidative activity Original Article heterocyclic compounds Quercetin Kaempferol Anti-HBsAg Two-dimensional nuclear magnetic resonance spectroscopy |
| Zdroj: | Journal of Traditional and Complementary Medicine Journal of Traditional and Complementary Medicine, Vol 1, Iss 1, Pp 57-63 (2011) |
| ISSN: | 2225-4110 |
| DOI: | 10.1016/s2225-4110(16)30057-8 |
| Popis: | Two new flavonol glucuronides, quercetin 3-O- β - d -2″-acetylglucuronide ( 1 ) and quercetin 3-O- β - d -2″-acetylglucuronide methyl ester ( 2 ), along with four known flavonoids ( 3 - 6 ) were isolated from the whole parts of Rotala rotundifolia . The structures of 1 and 2 were elucidated by application of various spectroscopic methods, including 1D and 2D NMR techniques. Biological evaluation showed that all of isolated flavonoid compounds have potent anti-oxidative activities by DPPH and superoxide anion methods, and kaempferol ( 3 ) and quercetin ( 4 ) exhibited significant anti-HBV activity assayed by anti-HBsAg production. The HPLC fingerprint with photodiode array detection (HPLC-DAD) for quality control of R. rotundifolia partitioned EtOAc layer was also established. |
| Databáze: | OpenAIRE |
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