Therapeutic non-invasive brain stimulation in amyotrophic lateral sclerosis: rationale, methods, and experience
| Autor: | Evan C Edmond, Martin R Turner, Charlotte J. Stagg |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Stimulation
Inhibitory postsynaptic potential Transcranial Direct Current Stimulation 03 medical and health sciences Therapeutic approach 0302 clinical medicine medicine Humans Amyotrophic lateral sclerosis Pathological 030304 developmental biology 0303 health sciences business.industry Amyotrophic Lateral Sclerosis Brain Neurophysiology medicine.disease Transcranial Magnetic Stimulation Psychiatry and Mental health Brain stimulation Excitatory postsynaptic potential Surgery Neurology (clinical) business Neuroscience 030217 neurology & neurosurgery |
| Popis: | The neurodegenerative syndrome amyotrophic lateral sclerosis (ALS) is characterised by increased cortical excitability, thought to reflect pathological changes in the balance of local excitatory and inhibitory neuronal influences. Non-invasive brain stimulation (NIBS) has been shown to modulate cortical activity, with some protocols showing effects that outlast the stimulation by months. NIBS has been suggested as a potential therapeutic approach for disorders associated with changes in cortical neurophysiology, including ALS. This article reviews NIBS methodology, rationale for its application to ALS and progress to date. |
| Databáze: | OpenAIRE |
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