Symptomatic Pituitary Metastasis as Initial Manifestation of Renal Cell Carcinoma: Case Report and Review of Literature
| Autor: | Patrick Natter, Russell Fung, Raafat Makary, Gunjan Y Gandhi, K C Balaji |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Pituitary gland
medicine.medical_specialty business.industry Endocrinology Diabetes and Metabolism medicine.medical_treatment Levothyroxine Urology Case Report medicine.disease RC648-665 Nephrectomy Prolactin Diseases of the endocrine glands. Clinical endocrinology Metastasis 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Pituitary adenoma Renal cell carcinoma 030220 oncology & carcinogenesis Diabetes insipidus medicine business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Case Reports in Endocrinology, Vol 2020 (2020) Case Reports in Endocrinology |
| ISSN: | 2090-6501 |
| Popis: | Metastasis to the pituitary gland is extremely rare (∼2% of sellar masses). Clinical, biochemical, and radiologic characteristics of pituitary metastasis are poorly defined and can be difficult to diagnose before surgery. We present an unusual case with pituitary metastasis as the first manifestation of renal cell carcinoma (RCC). A 70-year-old male presented with acute onset of weakness, dizziness, diplopia, and progressively worsening headache. The initial CT head revealed a heterogeneous sellar mass measuring 2.8 × 1.9 × 1.7 cm. A follow-up MRI showed the sellar mass invading the right cavernous sinus. The presumptive diagnosis was a pituitary macroadenoma. Physical examination revealed bilateral 6th cranial nerve palsy and episodes of intermittent binocular horizontal diplopia. Hormonal testing noted possible secondary adrenal insufficiency (AM serum cortisol: 3.3 mcg/dL, ACTH: 8 pg/mL), secondary hypothyroidism (TSH |
| Databáze: | OpenAIRE |
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