Neurosarcoidosis Associated with Psychiatric Symptoms: Case Report

Autor: Paulo Henrique Pires de Aguiar, Juliano Nery Navarro, Wolnei Marques Zeviani, Telmo Augusto Barba Belsuzarri, Maick Wilen Fernandes Neves, João Flavio de Araújo Mattos, Leticia Marissol de Souza Francisco, Renata de Melo Braga Marques
Rok vydání: 2017
Předmět:
Zdroj: Brazilian Neurosurgery, Vol 36, Iss 03, Pp 185-189 (2017)
ISSN: 2359-5922
0103-5355
DOI: 10.1055/s-0037-1606290
Popis: Background Sarcoidosis is a granulomatous disease predominant in women and black men that has inflammatory origin of unknown etiology; neurosarcoidosis is a rare and critical presentation of the disease. Case description A 26-year-old black female presented frontal headache for 1 year, as well as behavioral and mood changes for 15 days. Skull tomography and nuclear magnetic imaging of the skull revealed damaged meninges, a right frontal bone lesion, and an intraparenchymal contrast-enhancing lesion. Screening with computed tomography (CT) scans was performed, and it showed signs of bronchiectasis in the lower third of the right lung, but it was asymptomatic. The biopsy showed signs of reactional lesion with the presence of non-caseating granulomas. After the treatment with corticosteroids, the patient presented progressive improvement. Conclusions Neurosarcoidosis is a rare and critical pathology of sarcoidosis that presents a lytic bone lesion and clinical psychiatric symptoms; neurosarcoidosis is also rare in the literature.
Databáze: OpenAIRE