Pulmonary vein stenosis of ex-premature infants with pulmonary hypertension and bronchopulmonary dysplasia, epidemiology, and survival from a multicenter cohort
| Autor: | Jeffrey R. Fineman, A. Rebecca Kameny, Ivan M. Rebeyka, Linda Mahgoub, Christopher A. Calderone, Rachel D. Vanderlaan, Tarek Kaddoura, María Jesús del Cerro, Andrew N. Redington, Ashok Kakadekar, Ian Adatia, Frank Dicke, Paloma Lopez Ortego |
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| Rok vydání: | 2017 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine Cardiac Catheterization medicine.medical_specialty Hypertension Pulmonary medicine.medical_treatment 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Internal medicine medicine Humans Child Pulmonary vein stenosis Bronchopulmonary Dysplasia Retrospective Studies Cardiac catheterization business.industry Infant Newborn Infant Gestational age Retrospective cohort study medicine.disease Magnetic Resonance Imaging Pulmonary hypertension Surgery Stenosis Stenosis Pulmonary Vein Bronchopulmonary dysplasia Echocardiography Pulmonary Veins Child Preschool Pediatrics Perinatology and Child Health Cardiology Small for gestational age Female Tomography X-Ray Computed business Infant Premature |
| Zdroj: | Pediatric Pulmonology. 52:1063-1070 |
| ISSN: | 8755-6863 |
| Popis: | Background Pulmonary vein stenosis is emerging as an important clinical problem in ex-premature infants. Methods We sought to describe the epidemiology of pulmonary vein stenosis affecting ex-premature infants by a multicenter retrospective cohort study of patients from seven children's hospitals diagnosed between 2000-2014. Results We identified 39 ex-premature patients (26 males, median gestational age 28 weeks range 22-36 weeks, birth weight 1.1 kg range 433-2645–g) with pulmonary vein stenosis. Median age at diagnosis was 6.5 months (1 month-6 years). Presentation with pulmonary hypertension occurred in 26/39 (67%) and 29/39 (74%) had bronchopulmonary dysplasia, 15 (39%) were born of twin pregnancies with unaffected twin siblings. A median of 5 (range 1-25) echocardiograms was performed prior to diagnosis. The diagnosis was made using echocardiography in 22/39 (56%), by multi-detector contrast computed tomography scan (CT) in 8/39 (21%), cardiac catheterization in 6/39 (15%) patients, magnetic resonance imaging in 3/39 (8%). Freedom from death or re-stenosis was 73% at 1-year, 55% at 2, 5, and 10 years. Factors associated with shorter survival or re-stenosis were stenosis of ≥3 pulmonary veins (P |
| Databáze: | OpenAIRE |
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