Ciliated muconodular papillary tumors of the lung: Cytologic features and diagnostic pitfalls in intraoperative examinations
| Autor: | Hirokuni Kakinuma, Raito Maruyama, Yukitoshi Satoh, Masashi Mikubo, Tsutomu Yoshida |
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| Rok vydání: | 2018 |
| Předmět: |
Male
Pathology medicine.medical_specialty Histology Lung Neoplasms 030209 endocrinology & metabolism Pathology and Forensic Medicine Diagnosis Differential 03 medical and health sciences 0302 clinical medicine Cytology Medicine Humans Nuclear atypia Cilia Lung cancer Histiocyte Aged Lung business.industry Papillary tumor Solitary Pulmonary Nodule Nodule (medicine) General Medicine medicine.disease Adenocarcinoma Mucinous Carcinoma Papillary medicine.anatomical_structure 030220 oncology & carcinogenesis medicine.symptom business Wedge resection (lung) |
| Zdroj: | Diagnostic cytopathology. 47(7) |
| ISSN: | 1097-0339 |
| Popis: | Ciliated muconodular papillary tumors (CMPTs) of the lung are rare, likely benign neoplastic lesions. Here we describe a case of a CMPT, focusing on its cytologic features, which to our knowledge have not been reported previously. Owing to dull back pain, a 69-year-old male non-smoker underwent CT, which revealed a 1.3 × 1.3-cm solid nodule in the peripheral field of the left lower lung lobe. A wedge resection of the nodule was performed, with the provisional diagnosis being primary lung cancer. Macroscopic examination of a resected specimen showed a 1.2-cm grayish nodule. Touch imprint smear cytology revealed ciliated columnar cells and mucous cells, as well as abundant extracellular mucin on inflammatory background of lymphocytes and histiocytes. Histologic examination revealed a nodular papillary tumor composed of ciliated columnar cells, mucous cells, and basal cells surrounded by a mucin pool. No nuclear atypia or mitotic figures were identified. The final diagnosis was CMPT. The postoperative course was uneventful, with no recurrence at 8 months after surgery. Although a CMPT is a rare lung tumor, it should be considered when cytological or histological examination of a solitary peripheral lung nodule shows non-atypical ciliated cells and mucous cells surrounded by mucin. |
| Databáze: | OpenAIRE |
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