Simulation of the expected performance of INSERT: A new multi-modality SPECT/MRI system for preclinical and clinical imaging
| Autor: | Filippo Schembari, Carlo Fiorini, Paolo Busca, Kjell Erlandsson, M. Occhipinti, Gábor Németh, A. D. Butt, Peter Major, Paolo Trigilio, R. Quaglia, Brian Hutton, R. Peloso |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Physics
Nuclear and High Energy Physics medicine.medical_specialty Silicon drift detector sezele business.industry Detector Field of view Scintillator equipment and supplies law.invention Silicon photomultiplier law medicine Computer vision Medical physics Artificial intelligence business Instrumentation Image resolution Preclinical imaging Gamma camera |
| Popis: | A new multi-modality imaging tool is under development in the framework of the INSERT (INtegrated SPECT/MRI for Enhanced Stratification in Radio-chemo Therapy) project, supported by the European Community. The final goal is to develop a custom SPECT apparatus, that can be used as an insert for commercially available MRI systems such as 3 T MRI with 59 cm bore diameter. INSERT is expected to offer more effective and earlier diagnosis with potentially better outcome in survival for the treatment of brain tumors, primarily glioma. Two SPECT prototypes will be developed, one dedicated to preclinical imaging, the second one dedicated to clinical imaging. The basic building block of the SPECT detector ring is a small 5 cm×5 cm gamma camera, based on the well-established Anger architecture with a continuous scintillator readout by an array of silicon photodetectors. Silicon Drift Detectors (SDDs) and Silicon PhotoMultipliers (SiPM) are being considered as possible scintillator readout, considering that the detector choice plays a predominant role for the final performance of the system, such as energy and spatial resolution, as well as the useful field of view of the camera. Both solutions are therefore under study to evaluate their performances in terms of field of view (FOV), spatial and energy resolution. Preliminary simulations for both the preclinical and clinical systems have been carried out to evaluate resolution and sensitivity. |
| Databáze: | OpenAIRE |
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