Antiphospholipid Syndrome and Stroke

Autor: Kathryn, Grimes, P., Klein, Adam, Rakhee, Lalla, Adeolu, Morawo, Sana, Somani, J., Woodward, Mathew, W., Cole, John
Rok vydání: 2022
Předmět:
Zdroj: Antiphospholipid Syndrome-Recent Advances in Clinical and Basic Aspects
DOI: 10.5772/intechopen.101777
Popis: Thromboses of the cerebral arterial and venous systems are a common manifestation of antiphospholipid syndrome (APS) often leading to ischemic and hemorrhagic stroke. APS increases stroke risk via many mechanisms, including hypercoagulability and inflammation. These mechanisms, among others, must be considered by physicians when evaluating and treating such patients to achieve optimal short- and long-term outcomes. In this chapter, we will discuss the epidemiology of APS as it relates to neurological disease focusing on stroke, APS stroke mechanisms, suggested clinical evaluations, acute treatment strategies, and long-term secondary stroke prevention strategies. Current consensus statements and the most recent literature will be summarized.
Databáze: OpenAIRE