Post-traumatic endophthalmitis caused by streptococcus species in preschool children: clinical features, antibiotic susceptibilities and outcomes
| Autor: | Yujie Li, Zhaoxin Jiang, Wenjun Sui, Fang Duan, Jieting Zeng, Yao Yang, Xiaofeng Lin, Zhaohui Yuan, Manli Liu |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty medicine.drug_class Antibiotics Visual Acuity medicine.disease_cause Trauma Article Eye Infections Bacterial Endophthalmitis Levofloxacin Internal medicine Vitrectomy Streptococcus pneumoniae medicine Humans Child Eye diseases Retrospective Studies Cefuroxime Streptococcus business.industry Infant Retrospective cohort study medicine.disease Anti-Bacterial Agents Ophthalmology Child Preschool Infectious diseases Female Ofloxacin business medicine.drug |
| Zdroj: | Eye |
| ISSN: | 1476-5454 0950-222X |
| Popis: | Background/Objectives Streptococcus is a common cause of post-traumatic endophthalmitis in children. This study aimed to analyse the clinical features, antibiotic susceptibilities and outcomes of traumatic endophthalmitis caused by streptococcus in preschool children. Subjects/Methods Patients aged ≤6 years with traumatic streptococcal endophthalmitis seen at Zhongshan Ophthalmic Center between January 2013 and December 2018 were included in this retrospective study. Results In total, 21 patients (21 eyes) were included. The mean age of the patients was 3.3 ± 1.7 years, where 57.1% were males. Scissors (28.6%, n = 6) were the most common cause of injury; 86.7% of patients were injured at home. Zone I (80.9%) was the most common wound site; 90.5% of patients presented with a traumatic cataract. In general, Streptococcus pneumoniae (47.6%) was the most common isolate. Viridans group streptococci accounted for 58.3% of cases in children aged 0–3 years, while S. pneumoniae accounted for 66.7% of cases in children aged 4–6 years. The susceptibility rates of streptococcus to cefuroxime, levofloxacin and ofloxacin were 100%, 95.0% and 90.5%, respectively. Although all the patients underwent vitrectomy combined with silicone oil tamponade, the final visual outcomes were no better than counting fingers. Conclusions Although S. pneumoniae was the most prevalent organism in general, the dominant species varied between different age groups. The commonly used antibiotics, cefuroxime and fluoroquinolone, showed higher antibiotic susceptibility. Despite prompt treatment, the visual outcomes of paediatric post-traumatic endophthalmitis in preschool children were poor. |
| Databáze: | OpenAIRE |
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