An educational intervention about the classification of penicillin allergies: effect on the appropriate choice of antibiotic therapy in pregnant women
Autor: | C. Catteau, Bruno Grandbastien, P. Richart, A. Prevotat, D. Poitrenaud, C. Thellier, A. Beaugendre, Karine Faure, Damien Subtil, D. Pelletier de Chambure, R. Le Guern |
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Přispěvatelé: | Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Evaluation des technologies de santé et des pratiques médicales - ULR 2694 (METRICS), Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Service de Pneumologie et Immuno-Allergologie [CHU LIlle], Pole Cardio-vasculaire et pulmonaire [CHU Lille], Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Recherche translationelle relations hôte-pathogènes, Centre d’Infection et d’Immunité de Lille - INSERM U1019 - UMR 9017 - UMR 8204 (CIIL), Centre National de la Recherche Scientifique (CNRS)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Université de Lille-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Centre Hospitalier Régional Universitaire [Lille] [CHRU Lille], Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS], Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 [CIIL], CHU Lille, CNRS, Inserm, Institut Pasteur de Lille, Université de Lille, Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Université de Lille, Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 (CIIL), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), Le Guern, Rémi, Centre d'Infection et d'Immunité de Lille (CIIL) - U1019 - UMR 8204 |
Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
medicine.medical_specialty
Allergy Penicillin allergy medicine.drug_class [SDV]Life Sciences [q-bio] Antibiotics Cefazolin Penicillins [SDV.MHEP.GEO]Life Sciences [q-bio]/Human health and pathology/Gynecology and obstetrics Drug Hypersensitivity 03 medical and health sciences 0302 clinical medicine Patient Education as Topic Pregnancy 030202 anesthesiology Internal medicine Intervention (counseling) Antibiotic therapy medicine Humans 030212 general & internal medicine Medical prescription [SDV.IMM.ALL]Life Sciences [q-bio]/Immunology/Allergology Educational intervention Clindamycin business.industry Obstetrics and Gynecology medicine.disease Anti-Bacterial Agents 3. Good health Penicillin [SDV.MHEP.GEO] Life Sciences [q-bio]/Human health and pathology/Gynecology and obstetrics Anesthesiology and Pain Medicine [SDV.SP.PHARMA] Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology Female Pregnant Women business [SDV.IMM.ALL] Life Sciences [q-bio]/Immunology/Allergology medicine.drug |
Zdroj: | International Journal of Obstetric Anesthesia International Journal of Obstetric Anesthesia, Elsevier, 2020, International journal of obstetric anesthesia, 41, pp.22-28. ⟨10.1016/j.ijoa.2019.07.005⟩ International Journal of Obstetric Anesthesia, 2020, International journal of obstetric anesthesia, 41, pp.22-28. ⟨10.1016/j.ijoa.2019.07.005⟩ |
ISSN: | 0959-289X |
Popis: | International audience; BACKGROUND: Most pregnant women who self-report penicillin allergy are not truly penicillin-allergic and this misunderstanding often leads to administration of inappropriate antibiotic therapy. Decision algorithms have been developed to guide antibiotic selection but major discrepancies have been reported between guidelines and clinical practice. We aimed to optimize the prescription of antibiotics for pregnant women who self-reported penicillin allergy, using an educational intervention about the classification of penicillin allergies that targeted gynecologists, anesthesiologists and midwives.METHODS: This quasi-experimental study assessed the effect of an educational intervention about the classification of penicillin allergy. For six months, a combination of two strategies was used, namely dissemination of printed educational materials and group education. The principal study endpoint was the appropriateness of the antibiotic therapy, defined in advance for each level of allergic risk.RESULTS: The pre-intervention phase included 903 women; one year after its conclusion, the post-intervention phase began and included 892 women. The prevalence of self-reported penicillin allergy was stable over the two periods (6.8% before vs 5.4% after, P=0.24). The clinical classification of penicillin allergies was more often used after the educational intervention (68% vs 100%, P |
Databáze: | OpenAIRE |
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