Antimicrobial Activity of Hybrid Nanomaterials Based on Star and Linear Polymers of N,N′-Dimethylaminoethyl Methacrylate with In Situ Produced Silver Nanoparticles
| Autor: | Alicja Utrata-Wesołek, Anna Sotirova, Neli Koseva, Violeta Mitova, Natalia Oleszko-Torbus, Agnieszka Kowalczuk, Paulina Teper, Barbara Mendrek |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
silver nanoparticles
star polymers 02 engineering and technology 010402 general chemistry Methacrylate 01 natural sciences lcsh:Technology Silver nanoparticle Nanomaterials chemistry.chemical_compound Bromide Zeta potential General Materials Science lcsh:Microscopy lcsh:QC120-168.85 chemistry.chemical_classification poly(N N’-dimethylaminoethyl methacrylate) silver nanoparticles Aqueous solution antimicrobial activity lcsh:QH201-278.5 Chemistry lcsh:T Polymer 021001 nanoscience & nanotechnology 0104 chemical sciences lcsh:TA1-2040 lcsh:Descriptive and experimental mechanics poly(N N′-dimethylaminoethyl methacrylate) lcsh:Electrical engineering. Electronics. Nuclear engineering 0210 nano-technology Antibacterial activity lcsh:Engineering (General). Civil engineering (General) lcsh:TK1-9971 Nuclear chemistry |
| Zdroj: | Materials, Vol 13, Iss 3037, p 3037 (2020) Materials Volume 13 Issue 13 |
| ISSN: | 1996-1944 |
| Popis: | Well-defined linear and multi-arm star polymer structures were used as the templates for in situ synthesis and stabilization of silver nanoparticles (AgNPs). This approach led to hybrid nanomaterials with high stability and antibacterial activity to both Gram-positive and Gram-negative bacterial strains. The ecologically friendly so called &ldquo green&rdquo synthesis of nanomaterials was performed through AgNPs preparation in the aqueous solutions of star and linear poly(N,N&rsquo dimethylaminoethyl methacrylate)s (PDMAEMAs) the process was followed with time. The size, shape, and zeta potential of the obtained hybrids were determined. To our knowledge, this is the first time that the antibacterial activity of PDMAEMA hybrid nanomaterial against Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa was investigated and assessed by minimum inhibitory concentration (MIC) and minimum biocidal concentration (MBC). Completely quaternized with ethyl bromide, star and linear PDMAEMAs were used in comparative biological tests. The modification of the polymers with in situ-formed AgNPs increased the antibacterial properties against all studied strains of bacteria by several times in comparison to non-modified polymers and quaternized polymers. These results yield novel nanohybrid materials that can be useful for applications in medicine and biology. |
| Databáze: | OpenAIRE |
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