Novel thiol- and thioether-containing amino acids: cystathionine and homocysteine families
| Autor: | Luigi Longobardo, Nunzia Cecere, Marina DellaGreca, Ivan de Paola |
|---|---|
| Přispěvatelé: | Longobardo, Luigi, Nunzia, Cecere, DELLA GRECA, Marina, Ivan de, Paola |
| Rok vydání: | 2012 |
| Předmět: |
chemistry.chemical_classification
Aspartic Acid Molecular Structure biology Homocysteine Chemistry Stereochemistry Organic Chemistry Clinical Biochemistry Glutamic Acid chemistry.chemical_element Biochemistry Cystathionine beta synthase Sulfur Amino acid chemistry.chemical_compound Cystathionine Thioether Nucleophile Aspartic acid biology.protein Thiol |
| Zdroj: | Amino Acids. 44:443-448 |
| ISSN: | 1438-2199 0939-4451 |
| DOI: | 10.1007/s00726-012-1352-5 |
| Popis: | Natural L-homocysteine and L,L-cystathionine, along with a series of unnatural analogues, have been prepared from L-aspartic and L-glutamic acid. Manipulation of the protected derivatives provided ω-iodoamino acids, which were used in thioalkylation reactions of sulfur nucleophiles, such as the ester of L-cysteine and potassium thioacetate. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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