A new bioinformatics paradigm for the theory, research, and practice of therapeutic hypnosis
| Autor: | Bhaskar Vyas, Bruce Gregory, Stanley Krippner, Ernest Lawrence Rossi, Jane Mortimer, Richard Hill, Michael Shaffran, Salvatore Iannotti, David Atkinson, Margaret Bullock, Thierry Kallfass, Michel Kerouac, April Cybelle Rossi, Jorge Cuadros, Mauro Cozzolino, Claude Virot, Ella Soleimany, Erika Chovanec, Stefano Castiglione, Alessia Chiamberlando, Claire Frederick, Angela Cicatelli, Kathryn Rossi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Genetic Research
medicine.medical_specialty Hypnosis Psychotherapist medicine.medical_treatment media_common.quotation_subject Alternative medicine Translational research Translational Research Biomedical Excellence Intervention (counseling) medicine Humans Meaning (existential) Oligonucleotide Array Sequence Analysis media_common Inflammation Neuronal Plasticity Cognitive Behavioral Therapy epigenetics business.industry Keywords: Bioinformatics DNA microarrays hypnosis mind-body communication Gene Expression Profiling Stem Cells Brain Computational Biology General Medicine Mental health Up-Regulation Oxidative Stress Gene Expression Regulation Complementary and alternative medicine Cognitive therapy business Software |
| Zdroj: | Scopus-Elsevier |
| Popis: | In a 2008 pilot study we used DNA microarrays to explore the historical ideo-plastic faculty of therapeutic hypnosis. We documented how to measure changes in activity or experience-dependent gene expression over relatively brief time periods (1 hour and 24 hours) following a single intervention of therapeutic hypnosis (about 1 hour). In the present paper we utilize bioinformatic software to explore the possible meaning and significance of this ideo-plastic faculty of therapeutic hypnosis. Indications suggest that the ideo-plastic process of therapeutic hypnosis may be associated with (1) the heightening of a molecular-genomic signature for the up-regulation (heightened activity) of genes characteristic of stem cell growth, (2) a reduction in cellular oxidative stress, and (3) a reduction in chronic inflammation. We identify these three empirical associations as an initial beta version of the molecular-genomic signature of the ideo-plastic process of therapeutic hypnosis, which can serve as a theoretical and practical guide for clinical excellence by beginners as well as senior professionals. We propose this molecular-genomic level of discourse as a supplement to the traditional cognitive-behavioral description of therapeutic suggestion, hypnosis, and psychotherapy that is consistent with "translational research" currently funded by the National Institute of Mental Health (NIMH). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|