Intracerebellar malignant nerve sheath tumor in a child: case report and review of literature
| Autor: | Krishna C Joshi, Nirmala Subramanian, Hariprakash Chakravarthy |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Ataxia medicine.medical_treatment Histogenesis Nerve Sheath Neoplasms medicine Humans Cerebellar Neoplasms Child business.industry General Medicine medicine.disease Surgery Natural history Radiation therapy Nerve sheath tumor Treatment Outcome Radiological weapon Pediatrics Perinatology and Child Health Immunohistochemistry Female Neurology (clinical) Neurosurgery medicine.symptom business |
| Zdroj: | Child's Nervous System. 31:785-788 |
| ISSN: | 1433-0350 0256-7040 |
| DOI: | 10.1007/s00381-014-2532-2 |
| Popis: | Intracerebellar malignant nerve sheath tumor (ICMNST) is an extremely rare entity, only two cases have been reported previously, and this is the first case to be reported in a child. The histogenesis, diagnosis, and management of this entity are very ambiguous, and natural history in a child is unknown. The authors report a 7-year-old girl who presented with ataxia and signs of raised intracranial pressure and discuss the challenges in diagnosis, surgical strategy, and treatment. Following gross total resection and radiation to tumor bed, the patient had unremarkable recovery and is recurrence free at 1-year follow-up. ICMNSTs are extremely rare tumors of the cerebellum. Preoperative radiological diagnosis is not possible due to its close radiological resemblance to other common posterior fossa tumors. Immunohistochemistry plays a pivotal role in clinching the diagnosis. Though the reported adult counterparts have shown dismal prognosis, the pediatric counterparts may fare better with good surgical resection followed by radiotherapy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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