Oral health in Alzheimer’s disease: a multicenter case-control study
| Autor: | M A Zea-Sevilla, Ricardo Corral, F Aragón, Belén Frades-Payo, Carmen Tejedor, Javier Montero, Vanessa Paredes-Gallardo, Alberto Albaladejo, Pilar Sancho |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Saliva Oral Health Disease Oral health Oral hygiene 03 medical and health sciences 0302 clinical medicine Alzheimer Disease Internal medicine medicine Tooth loss Humans Geriatric Assessment General Dentistry Aged Aged 80 and over business.industry Incidence (epidemiology) Case-control study 030206 dentistry Middle Aged medicine.disease Spain Case-Control Studies Female Alzheimer's disease medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Clinical Oral Investigations. 22:3061-3070 |
| ISSN: | 1436-3771 1432-6981 |
| DOI: | 10.1007/s00784-018-2396-z |
| Popis: | The aim of this case-control study was to carry out an oral health assessment on a group of Alzheimer’s patients and to establish a hypothesis regarding the implication of the characteristics of the disease and the treatment of oral health. A total of 70 Alzheimer’s patients, residents at the Alzheimer Center Reina Sofia Foundation (Madrid, Spain) and at the Alzheimer State Reference Center (Salamanca, Spain), and 36 controls (companions/acquaintances), were studied by oral examination and saliva sampling. The oral health indices DMFT/DMFS, CPI, the prosthetic condition, oral hygiene, saliva volume, and pH, as well as the specific microbiological parameters governing the risk of developing caries were assessed. Alzheimer’s patients exhibited, as compared to the control group, (1) fewer teeth (10.9 ± 10.5 vs 23.7 ± 6.5), (2) fewer obturations (2.2 ± 3.4 vs 6.6 ± 5.6), (3) fewer periodontally healthy sextants (0.1 ± 0.4 vs 1.4 ± 2.2), (4) worse oral hygiene (43.1 vs 72.2% brushed), (5) greater use of removable prostheses (47.8 vs 8.4%), (6) higher incidence of candida infection (11.8 vs 0.0%) and cheilitis (15.9 vs 0.0%), (7) lower salivary flow (0.6 ± 0.6 vs 1.1 ± 0.6), and (8) lower buffering capacity (46 vs 80%). After taking into account the influence of age, Alzheimer’s patients had worse oral health (caries and periodontal disease), more mucosal lesions (cheilitis and candidiasis), and worse saliva quantity and quality. Clinicians should be aware of the implications of Alzheimer’s disease in oral health, in order to stablish the effective preventive measures and the optimal treatment plan. |
| Databáze: | OpenAIRE |
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