Adenovirus related lymphohistiocytic hemophagocytosis: Case report and literature review
| Autor: | Olivier Aoun, A. Laparra, M. Sanson, Eric Caumes, J. Mayaux, David Boutolleau, Guillaume Mellon, B. Henry |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
0301 basic medicine Bone marrow transplant Pathology medicine.medical_specialty Adenoviridae Infections medicine.medical_treatment Antineoplastic Agents Astrocytoma Lymphohistiocytosis Hemophagocytic 03 medical and health sciences 0302 clinical medicine Drug Therapy Bone Marrow Virology medicine Brain Stem Neoplasms Humans In patient Chemotherapy business.industry Adenoviruses Human Hypertriglyceridemia Viral Load medicine.disease Pancytopenia Blood 030104 developmental biology Infectious Diseases 030220 oncology & carcinogenesis Female Hemophagocytosis business Viral load |
| Zdroj: | Journal of Clinical Virology. 78:53-56 |
| ISSN: | 1386-6532 |
| Popis: | Introduction Adenoviral infection is a classic cause of lymphohistiocytic hemophagocytosis (LH) in bone marrow transplantation but is rare outside this setting. Case report A 31-year-old female, with a history of treated mesencephalic astrocytoma, was hospitalized for fever, pancytopenia, elevated liver enzymes, hyperferritinemia and hypertriglyceridemia. Adenovirus viral load in blood was 7.3 × 10 9 copies/mL. Bone marrow aspirate examination confirmed LH. The patient recovered without specific LH or adenovirus-directed treatment. Conclusion Adenovirus-related LH, common in bone marrow transplant recipients, should also be considered in patients with chemotherapy in solid tumors. |
| Databáze: | OpenAIRE |
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