Three-Year Major Clinical Outcomes of Angiography-Guided Single Stenting Technique in Non-Complex Left Main Coronary Artery Diseases

Autor: Cheol Ung Choi, Sunki Lee, Yong Hoon Kim, Woohyeun Kim, Eung Ju Kim, Byoung Geol Choi, Sung Hun Park, Seung-Woon Rha, Chang Gyu Park, Ae Young Her, Seyeon Choi, Minsuk Shim, Eun Jin Park, Hong Seog Seo, Jun Hyuk Kang, Hu Li, Jae Kyeong Byun, Jin Oh Na, Dong Joo Oh, Jah Yeon Choi, Hong Euy Lim
Rok vydání: 2017
Předmět:
Male
medicine.medical_specialty
medicine.medical_treatment
Long Term Adverse Effects
Coronary Artery Disease
030204 cardiovascular system & hematology
Coronary Angiography
Revascularization
Severity of Illness Index
03 medical and health sciences
Percutaneous Coronary Intervention
0302 clinical medicine
Internal medicine
Republic of Korea
Intravascular ultrasound
medicine
Humans
cardiovascular diseases
030212 general & internal medicine
Myocardial infarction
Ultrasonography
Interventional

Aged
medicine.diagnostic_test
business.industry
Percutaneous coronary intervention
Stent
Drug-Eluting Stents
General Medicine
Middle Aged
medicine.disease
Coronary Vessels
Survival Analysis
surgical procedures
operative

Surgery
Computer-Assisted

Angiography
Conventional PCI
Cardiology
Female
Cardiology and Cardiovascular Medicine
business
Mace
Follow-Up Studies
Zdroj: International Heart Journal. 58:704-713
ISSN: 1349-3299
1349-2365
DOI: 10.1536/ihj.17-115
Popis: There is limited long-term comparative clinical outcome data concerning angiography- versus intravascular ultrasound (IVUS)-guided percutaneous coronary intervention (PCI) in non-complex left main coronary artery (LMCA) disease treated with the single stenting technique in the drug-eluting stent (DES) era.The aim of this study was to investigate whether angiography-guided stenting is comparable to IVUS-guided stenting during 3-year clinical follow-up periods in patients with non-complex LM disease treated with the single stenting technique.A total of 196 patients treated with either angiography-guided (n = 74) or IVUS-guided (n = 122) PCI were included. The primary outcome was the occurrence of major adverse cardiac events (MACE) defined as total death, non-fatal myocardial infarction (MI), target lesion revascularization (TLR), target vessel revascularization (TVR), and non-target vessel revascularization (Non-TVR). To adjust for any potential confounders, propensity score (PS) adjusted analysis was performed.During 3-year follow-up, the PS adjusted Cox-proportional hazard ratio (HR) was not significantly different between the two groups for total death, cardiac death, and MI. Also, TLR and the combined rates of TVR and non-TVR were not significantly different. Finally, MACE was not significantly different between the two groups (HR: 0.63, 95% Confidence interval (CI): 0.33-1.17; P = 0.149).Angiography-guided PCI for non-complex LMCA diseases treated with the single stenting technique showed comparable results compared with IVUS-guided PCI in reducing clinical events during 3-year clinical follow-up in the DES era. Although IVUS guided PCI is the ideal strategy, angiography-guided PCI can be an option for LMCA PCI in some selected cases.
Databáze: OpenAIRE