Comparison between myocardial function assessed by echocardiography during hospitalization for COVID-19 and at 4 months follow-up

Autor: B. van den Borst, T M H Eijsvogels, B. M. A. van Bakel, Anthonie L. Duijnhouwer, Robin Nijveldt, A.P.J. van Dijk, F.L. van de Veerdonk, A C Dimitriu-Leen, P C Koopmans, R R J van Kimmenade, J. Vos, Frank H. Bosch, Q. de Mast, F M A van den Heuvel
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Male
medicine.medical_specialty
Coronavirus disease 2019 (COVID-19)
Vascular damage Radboud Institute for Health Sciences [Radboudumc 16]
lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]
Subgroup analysis
030204 cardiovascular system & hematology
Single Center
Communicable Diseases
Healthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18]
03 medical and health sciences
0302 clinical medicine
Predictive Value of Tests
Internal medicine
medicine
Humans
Radiology
Nuclear Medicine and imaging
030212 general & internal medicine
Prospective Studies
Prospective cohort study
Cardiac imaging
Original Paper
Ejection fraction
business.industry
SARS-CoV-2
COVID-19
Stroke Volume
Stroke volume
Middle Aged
Hospitalization
lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4]
Echocardiography
Predictive value of tests
Cardiology
Myocardial function
Female
Cardiology and Cardiovascular Medicine
business
Follow-Up Studies
Zdroj: The International Journal of Cardiovascular Imaging
International Journal of Cardiovascular Imaging, 37, 3459-3467
International Journal of Cardiovascular Imaging, 37, 12, pp. 3459-3467
ISSN: 1875-8312
1569-5794
Popis: Contains fulltext : 244778.pdf (Publisher’s version ) (Open Access) In patients hospitalized for corona virus infectious disease 19 (COVID-19) it is currently unknown whether myocardial function changes after recovery and whether this is related to elevated cardiac biomarkers. In this single center, prospective cohort study we consecutively enrolled hospitalized COVID-19 patients between 1 April and 12 May 2020. All patients underwent transthoracic echocardiography (TTE) evaluation during hospitalization and at a median of 131 days (IQR; 116-136) follow-up. Of the 51 patients included at baseline, 40 (age: 62 years (IQR; 54-68), 78% male) were available for follow-up TTE. At baseline, 68% of the patients had a normal TTE, regarding left ventricular (LV) and right ventricular (RV) volumes and function, compared to 83% at follow-up (p = 0.07). Median LV ejection fraction (60% vs. 58%, p = 0.54) and tricuspid annular plane systolic excursion (23 vs 22 mm, p = 0.18) were comparable between hospitalization and follow-up, but a significantly lower RV diameter (39 vs. 34 mm, p = 0.002) and trend towards better global longitudinal strain (GLS) (- 18.5% vs - 19.1%, p = 0.07) was found at follow-up. Subgroup analysis showed no relation between patients with and without elevated TroponinT and/or NT-proBNP during hospitalization and myocardial function at follow-up. Although there were no significant differences in individual myocardial function parameters at 4 months follow-up compared to hospitalisation for COVID-19, there was an overall trend towards normalization in myocardial function, predominantly due to a higher rate of normal GLS at follow-up. 01 december 2021
Databáze: OpenAIRE
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