Characterization of Climbazole–Bovine serum albumin interaction by experimental and in silico approaches

Autor: Md. Zahirul KABIR, Hafsa TAYYAB, Cem ERKMEN, Sevinc KURBANOGLU, Saharuddin B. MOHAMAD, Bengi USLU
Rok vydání: 2023
Předmět:
Zdroj: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 288:122197
ISSN: 1386-1425
DOI: 10.1016/j.saa.2022.122197
Popis: Interactive association of an antifungal drug, climbazole (CBZ) with the carrier protein in bovine circulation, bovine serum albumin (BSA) was explored by fluorescence and absorption spectroscopy along with in silico techniques. The fluorescence and absorption spectral alterations of the protein upon addition of CBZ affirmed the complex foration between CBZ and BSA. The inverse temperature dependence behaviour of the K
Databáze: OpenAIRE