Serum trace element and heavy metal levels in patients with sepsis
| Autor: | Nevin Ince, Mehmet Ali Sungur, İdris Akkaş |
|---|---|
| Přispěvatelé: | [Belirlenecek] |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
Risk inorganic chemicals Turkey Organ dysfunction syndrome Iron critically ill 030232 urology & nephrology 030209 endocrinology & metabolism Zinc Supplementation Sepsis sepsis 03 medical and health sciences 0302 clinical medicine Immune system Metals Heavy Prevalence medicine Humans In patient Prospective Studies Mortality heavy metals Aged Aged 80 and over Trace elements Critically ill business.industry Trace element Heavy metals Middle Aged medicine.disease serum levels Oxidative Stress Damage Case-Control Studies Immunology Female Geriatrics and Gerontology business Biomarkers Copper Selenium Concentrations Cadmium |
| Popis: | Background and objectives: Sepsis is defined as a life-threatening organ dysfunction syndrome, which occurs when the body's immune response to infection is impaired. The aim of the present study was to investigate serum Iron, Copper, Zinco, Cobalt, Chromium, Selenium, Vanadium, Nickel, Cadmium, and Aliminium levels in patients with sepsis. Materials and methods: This prospective and observational study was conducted at a tertiary care university hospital of Turkey from 2015 to 2016, and comprised patients with sepsis. Serum concentrations of 10 elements were analyzed using inductively coupled plasma mass spectrometry. Analyses were performed at the laboratory of Duzce University Scientific and Technological Research Application and Research Center. A total of 87 participants (52 men, 35 women; average age, 74.11 +/- 14.26) were enrolled. Results: When evaluated in terms of trace elements, a significant difference was noted between the sepsis and control groups in terms of the levels of the five elements. Chromium, Iron, Nickel, Copper, and Cadmium levels were significantly higher in the sepsis group. Conclusion: Our study indicated in particular, Iron, Copper, Chromium, Nickel, and Cadmium levels were elevated in patients with sepsis. WOS:000520576100001 2-s2.0-85082319489 PubMed: 32183594 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|