The impact of nail psoriasis on disease activity, quality of life, and clinical variables in patients with psoriatic arthritis: A cross-sectional multicenter study
| Autor: | Gizem Cengiz, Kemal Nas, Yaşar Keskin, Erkan Kılıç, Betül Sargin, Sevtap Acer Kasman, Hakan Alkan, Nilay Sahin, Nihan Cüzdan Balta, İlknur Albayrak Gezer, Dilek Keskin, Cevriye Mülkoğlu, Hatice Reşorlu, Şebnem Ataman, Ajda Bal, Merve Baykul, Mehmet Tuncay Duruöz, Okan Küçükakkaş, Ozan Volkan Yurdakul, Meltem Alkan Melikoğlu, Fikriye Figen Ayhan, Hatice Bodur, Mustafa Çaliş, Erhan Çapkin, Gül Devrimsel, Kevser Gök, Sami Hizmetli, Ayhan Kamanlı, Hilal Ecesoy, Öznur Kutluk, Nesrin Şen, Ömer Faruk Şendur, İbrahim Tekeoğlu, Murat Toprak, Sena Tolu, Tiraje Tuncer |
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| Přispěvatelé: | KESKİN, Yaşar, CENGİZ G., Nas K., KESKİN Y., Kilic E., Sargin B., ACER KASMAN S., ALKAN H., ŞAHİN N., Balta N. C. , Gezer I. A. , et al. |
| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: |
Internal Diseases
Severity Index Epidemiology Distal Interphalangeal Joint Pathogenesis Recommendations Sağlık Bilimleri İmmünoloji ve Romatoloji Severity of Illness Index İç Hastalıkları Clinical Medicine (MED) Immunology and Rheumatology Ankylosing-Spondylitis Nail Diseases Rheumatology Health Sciences Onycholysis Prevalence Humans Psoriasis Klinik Tıp (MED) ROMATOLOJİ clinical characteristics Features psoriatic arthritis Internal Medicine Sciences Klinik Tıp Arthritis Psoriatic Dahili Tıp Bilimleri CLINICAL MEDICINE nail psoriasis Tıp Cross-Sectional Studies A cross-sectional multicenter study.- International journal of rheumatic diseases 2022 [Cengiz G. Nas K. Keskin Y. Kılıç E. Sargin B. Acer Kasman S. Alkan H. Sahin N. Cüzdan Balta N. Gezer İ. A. et al. -The impact of nail psoriasis on disease activity quality of life and clinical variables in patients with psoriatic arthritis] Quality of Life Medicine nail involvement Female Involvement Romatoloji disease activity |
| Popis: | © 2022 Asia Pacific League of Associations for Rheumatology and John Wiley & Sons Australia, Ltd.Aim: Nail involvement is common in psoriatic arthritis. This study assesses clinical characteristics, nail psoriasis prevalence, and impact of nail psoriasis on disease activity in patients with psoriatic arthritis (PsA). Method: This cross-sectional multicenter study was conducted by the Turkish League Against Rheumatism using PsA patients recruited from 25 centers. Demographic and clinical characteristics of PsA patients, such as disease activity measures, quality of life, and nail involvement findings were assessed during routine follow-up examinations. Patients were divided into two groups according to the presence or absence of nail psoriasis and compared using the χ2 test or Fisher exact test for categorical variables and the t-test or Mann-Whitney U test for continuous variables. Results: In 1122 individuals with PsA, 645 (57.5%) displayed nail psoriasis. The most frequent features of fingernails were ridges (38%), followed by pitting (21%) and onycholysis (19%). More females were present in both groups (with and without nail psoriasis; 64% vs 67%, P < 0.282). Patients with nail psoriasis were older, indicated more pain and fatigue, experienced greater swelling, tender joint counts, and skin disease severity, and had a higher disease activity score compared with those without nail psoriasis (all P < 0.05). Conclusion: We demonstrate an increased prevalence of nail psoriasis observed in patients with psoriatic arthritis. Patients with nail involvement experience increased disease activity, lower quality of life, and diminished mental and physical status compared with those without nail involvement. |
| Databáze: | OpenAIRE |
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