Complications and Risk after Mandibular Reconstruction with Fibular Free Flaps in Patients with Oral Squamous Cell Carcinoma: A Retrospective Cohort Study
| Autor: | Tymour Forouzanfar, J. N. Lodders, K.H. Karagozoglu, J. G. A. M. de Visscher, E.A.J.M. Schulten |
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| Přispěvatelé: | Maxillofacial Surgery (VUmc), Oral and Maxillofacial Surgery / Oral Pathology, MOVE Research Institute, CCA - Evaluation of Cancer Care, MKA Vumc (OII, ACTA) |
| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Comorbidity Mandibular Neoplasms 030230 surgery Free Tissue Flaps Tobacco Use 03 medical and health sciences Postoperative Complications 0302 clinical medicine SDG 3 - Good Health and Well-being Oral and maxillofacial pathology medicine Carcinoma Humans Fibula Netherlands Retrospective Studies Bone Transplantation business.industry Medical record Graft Survival Retrospective cohort study Middle Aged medicine.disease Surgery stomatognathic diseases Treatment Outcome 030220 oncology & carcinogenesis Carcinoma Squamous Cell Quality of Life Oral and maxillofacial surgery Female Mandibular Reconstruction business |
| Zdroj: | Lodders, J N, Schulten, E A J M, de Visscher, J G A M, Forouzanfar, T & Karagozoglu, K H 2016, ' Complications and risk after mandibular reconstruction with fibular free flaps in patients with oral squamous cell carcinoma: a retrospective cohort study ', Journal of Reconstructive Microsurgery, vol. 32, no. 6, pp. 455-463 . https://doi.org/10.1055/s-0036-1571794 Lodders, J N, Schulten, E A J M, de Visscher, J G A M, Forouzanfar, T & Karagozoglu, K H 2016, ' Complications and Risk after Mandibular Reconstruction with Fibular Free Flaps in Patients with Oral Squamous Cell Carcinoma: A Retrospective Cohort Study ', Journal of Reconstructive Microsurgery, vol. 32, no. 6, pp. 455-463 . https://doi.org/10.1055/s-0036-1571794 Journal of Reconstructive Microsurgery, 32(6), 455-463. Thieme Medical Publishers Inc. Journal of Reconstructive Microsurgery, 32(6), 455-463. Thieme Medical Publishers |
| ISSN: | 1098-8947 0743-684X |
| Popis: | Background. We retrospectively analyzed the incidence and types of postoperative complications after mandibular continuity reconstructions with fibular free flaps (FFF) in patients with oral squamous cell carcinoma (OSCC) and identified potential risk factors for postoperative complications.Methods. Data were retrieved from the medical records in the Department of Oral and Maxillofacial Surgery/Oral Pathology, VU University Medical Center/Academic Centre for Dentistry Amsterdam (ACTA), Amsterdam, The Netherlands from April 1995 to September 2013, and were statistically analyzed.Results. In this study, 85 patients were included in whom 86 FFFs were used for mandibular reconstruction. Thirty-seven patients (43%) developed ≥ 1 surgical complication and 9 patients (10.5%) developed ≥ 1 systemic complication. Three patients (3.5%) developed total flap failure and six patients (7.0%) developed partial flap failure. Surgical complications were correlated with tobacco use, partial glossectomy, type of mandibular defect, and anatomic staging. Systemic complications were associated with age > 60 years and Charlson comorbidity index > 2. Hospitalization > 30 days was associated with type of mandibular defect.Conclusions. The use of the FFF for reconstructing mandibular continuity defects in OSCC patients may be associated with postoperative complications. Patients with coexisting medical conditions and anterior mandibular defects have an increased risk for developing complications. Patients who undergo segmental mandibular resection including a partial glossectomy could have a reduced risk for complications. |
| Databáze: | OpenAIRE |
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