Induced tolerance to Schistosoma mansoni antigens modulates periovular granuloma

Autor: Rosella de Oliveira Santos, John R. David, Moysés Sadigursky, Maria de Fátima Falangola, S. A. Cardoso
Rok vydání: 1987
Předmět:
Zdroj: Memórias do Instituto Oswaldo Cruz, Volume: 82 Supplement 4, Pages: 269-271, Published: 1987
Memórias do Instituto Oswaldo Cruz., Vol 82, Pp 269-271 (1987)
ISSN: 0074-0276
Popis: Immunological tolerance to Schistosoma mansoni antigens induced by oral exposure of neonatal and adult mice to adult worm, soluble egg and polysaccharide antigens conducted to modulated periovular granuloma of infected mice. However the tolerance do not interfere in the infection. The estimative population and subpopulation of lymphocytes in the spleen of tolerized (not infected) animals do not differ from normal animals but Lyt 2.2 reactive lymphocytes to Schistosoma antigens was demonstrated in the tolerized animals.
Databáze: OpenAIRE