Recurrence of primary glomerulonephritis: Review of the current evidence
| Autor: | Fedaey Abbas, Ajay Sharma, Mohsen El Kossi, Jon Kim Jin, Ahmed Halawa |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Transplantation
medicine.medical_specialty business.industry medicine.medical_treatment Primary glomerulonephritis 030232 urology & nephrology Renal function Glomerulonephritis Immunosuppression Renal transplantation Review 030230 surgery medicine.disease Pathogenesis 03 medical and health sciences 0302 clinical medicine Epidemiology medicine Recurrent disease Intensive care medicine business Recurrent glomerulonephritis Dialysis |
| Zdroj: | World Journal of Transplantation |
| ISSN: | 2220-3230 |
| Popis: | In view of the availability of new immunosuppression strategies, the recurrence of allograft glomerulonephritis (GN) are reported to be increasing with time post transplantation. Recent advances in understanding the pathogenesis of the GN recurrent disease provided a better chance to develop new strategies to deal with the GN recurrence. Recurrent GN diseases manifest with a variable course, stubborn behavior, and poor response to therapy. Some types of GN lead to rapid decline of kidney function resulting in a frustrating return to maintenance dialysis. This subgroup of aggressive diseases actually requires intensive efforts to ascertain their pathogenesis so that strategy could be implemented for better allograft survival. Epidemiology of native glomerulonephritis as the cause of end-stage renal failure and subsequent recurrence of individual glomerulonephritis after renal transplantation was evaluated using data from various registries, and pathogenesis of individual glomerulonephritis is discussed. The following review is aimed to define current protocols of the recurrent primary glomerulonephritis therapy. |
| Databáze: | OpenAIRE |
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