Fever of unknown origin (FUO) on a land on cross-roads between Asia and Europa; a multicentre study from Turkey
| Autor: | Ercan Yenilmez, Elif Ozge Damar Midik, Sibel Yorulmaz Göktaş, Merve Kacar Eker, Seval Bilgic Atli, Hava Kaya, Zehra Karacaer, Deniz Kakalicoglu, Mine Filiz, Ilyas Dokmetas, Fatma Bozkurt, Aysegul Akkol Camurcu, Hande Berk Cam, Ersin Tural, Ahmet Z. Sahin, Sukran Kose, Halil Erkan, Eren Arkali, Levent Gorenek, Mehmet Reşat Ceylan |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
medicine.medical_specialty Asia Turkey Disease 030204 cardiovascular system & hematology Fever of Unknown Origin Thyroiditis 03 medical and health sciences 0302 clinical medicine Internal medicine Humans Medicine 030212 general & internal medicine Fever of unknown origin Aged Retrospective Studies business.industry Retrospective cohort study Brucellosis General Medicine medicine.disease Infective endocarditis Etiology Differential diagnosis business Still's Disease Adult-Onset |
| Popis: | AIMS The differential diagnosis of Fever of Unknown Origin (FUO) is still a major clinical challenge despite the advances in diagnostic procedures. In this multicentre study, we aimed to reveal FUO aetiology and factors influencing the final diagnosis of FUO in Turkey. METHODS A total of 214 patients with FUO between the years 2015 and 2019 from 13 tertiary training and research hospitals were retrospectively evaluated. RESULTS The etiologic distribution of FUO was infections (44.9%), malignancies (15.42%), autoimmune/inflammatory (11.68%) diseases, miscellaneous diseases (8.41%) and undiagnosed cases (19.62%). Brucellosis (10.25%), extrapulmonary tuberculosis (6.54%) and infective endocarditis (6.54%) were the most frequent three infective causes. Solid malignancies (7.1%) and lymphoma (5.6%), adult-onset still's disease (6.07%) and thyroiditis (5.14%) were other frequent diseases. The aetiological spectrum did not differ in elderly people (P |
| Databáze: | OpenAIRE |
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