Angiotensin-Induced Hypertension Chemotherapy in Children with Advanced Solid Tumors
Autor: | Yoshio Igarashi, Yasuo Horikoshi, Takako Chiba, Teruaki Hongo, Nobuko Furukawa, Shuhei Yajima, Yuji Fujii, Hiroyuki Masui, Hiroaki Nakajima, Kaoru Nasuda |
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Rok vydání: | 1991 |
Předmět: |
Male
Oncology Sacrum medicine.medical_specialty Hepatoblastoma Carcinoma Hepatocellular Lung Neoplasms Adolescent medicine.medical_treatment Bone Neoplasms Neoplasms Internal medicine Antineoplastic Combined Chemotherapy Protocols Renin–angiotensin system medicine Humans Child Infusions Intravenous Neoplasm Staging Chemotherapy Coccyx business.industry Angiotensin II Liver Neoplasms Infant Thoracic Neoplasms medicine.disease Pediatric cancer Child Preschool Hepatocellular carcinoma Hypertension Pediatrics Perinatology and Child Health Immunohistochemistry Female Sarcoma business |
Zdroj: | Pediatrics International. 33:381-383 |
ISSN: | 1442-200X 1328-8067 |
DOI: | 10.1111/j.1442-200x.1991.tb01570.x |
Popis: | Angiotensin-induced hypertension chemotherapy (IHC) was investigated in six children with the following advanced malignancies: hepatocellular carcinoma, extraskeletal Ewing's sarcoma, sacrococcygeal malignant teratoma, small round cell tumor of the chest wall, hepatoblastoma and osteogenic sarcoma. Partial response was achieved in three of these patients, two showed no change, and in one IHC was used as adjuvant chemotherapy. The side effects of IHC were minimal and tolerable. Angiotensin-IHC may provide a new approach to pediatric cancer chemotherapy. |
Databáze: | OpenAIRE |
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