Angiotensin-Induced Hypertension Chemotherapy in Children with Advanced Solid Tumors

Autor: Yoshio Igarashi, Yasuo Horikoshi, Takako Chiba, Teruaki Hongo, Nobuko Furukawa, Shuhei Yajima, Yuji Fujii, Hiroyuki Masui, Hiroaki Nakajima, Kaoru Nasuda
Rok vydání: 1991
Předmět:
Zdroj: Pediatrics International. 33:381-383
ISSN: 1442-200X
1328-8067
DOI: 10.1111/j.1442-200x.1991.tb01570.x
Popis: Angiotensin-induced hypertension chemotherapy (IHC) was investigated in six children with the following advanced malignancies: hepatocellular carcinoma, extraskeletal Ewing's sarcoma, sacrococcygeal malignant teratoma, small round cell tumor of the chest wall, hepatoblastoma and osteogenic sarcoma. Partial response was achieved in three of these patients, two showed no change, and in one IHC was used as adjuvant chemotherapy. The side effects of IHC were minimal and tolerable. Angiotensin-IHC may provide a new approach to pediatric cancer chemotherapy.
Databáze: OpenAIRE