Dengue fever as a potential cause of sickle cell intrahepatic cholestasis: A report of two cases
Autor: | Ana Laura Castro Costa, Sheila Soares-Silva, Paula Almeida, Leonardo Rodrigues de Oliveira, Vanessa Afonso da Silva, Luzia Beatriz Ribeiro Zago |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Microbiology (medical)
medicine.medical_specialty Anemia Endothelial cells Cell RC955-962 Case Report Disease Gastroenterology Dengue fever Dengue Cholestasis Internal medicine Arctic medicine. Tropical medicine medicine Sickle Cell Diseases business.industry Sickle cell disease Organ dysfunction Jaundice medicine.disease Infectious Diseases medicine.anatomical_structure Parasitology medicine.symptom business |
Zdroj: | Revista da Sociedade Brasileira de Medicina Tropical, Vol 54 (2021) Revista da Sociedade Brasileira de Medicina Tropical |
ISSN: | 1678-9849 |
Popis: | Sickle cell intrahepatic cholestasis is a potentially fatal syndrome characterized by jaundice, painful hepatomegaly, and organ dysfunction. Two cases of sickle cell intrahepatic cholestasis associated with dengue fever were described. Endothelial damage/dysfunction is a mechanism involved in severe hepatobiliary complications related to sickle cell diseases. However, the reasons for the lack of increase in the admission of patients with sickle cell disease having severe acute hepatobiliary complications triggered by endothelial damage/dysfunction due to dengue fever remain unknown. This study describes the first association between sickle cell intrahepatic cholestasis and dengue fever. |
Databáze: | OpenAIRE |
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