Alteration of anxiety and depression after awake craniotomy: a prospective study on patients with language eloquent high-grade glioma
| Autor: | Amirhossein Larijani, Ahmad Pour-Rashidi, Mostafa Farzin, Mohammad Arbabi, Mohammad Rahmani, Hamideh Ajam, Maysam Alimohamadi, Kasra Hendi |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
business.industry medicine.disease Hospital Anxiety and Depression Scale Checklist Awake craniotomy Glioma Internal medicine medicine Anxiety Surgery Neurology (clinical) medicine.symptom Prospective cohort study business Depression (differential diagnoses) High-Grade Glioma |
| Zdroj: | Journal of Neurosurgical Sciences. |
| ISSN: | 1827-1855 |
| Popis: | Background Awake Craniotomy (AC) is considered to achieve maximal safe resection of language eloquent gliomas. Impact of AC on the psychological status of patients (mainly anxiety, and post-traumatic stress disorder: PTSD) is a potential concern. Despite the studies reporting the early postoperative patient's perception after AC, this study has been performed to quantitatively evaluate the long term influence of AC on the level of anxiety/depression after surgery. Methods Patients who underwent AC for suspected language eloquent high-grade glioma were enrolled in this study. The anxiety, depression and PTSD of the patients were evaluated via hospital anxiety and depression scale (HADS) one week before and 1 and 6 months after the operation. PTSD symptoms were assessed according to the DSM-V checklist and confirmed by a structured clinical interview for DSM-V. Results Twenty-eight patients (22 men, 6 women) with the mean age of 39.2 years were enrolled. The mean preoperative depressive and anxiety score was 4.9±5.9 and 7.7±5.8 respectively. One month after surgery they were 6±4.9 and 7.4±6.2 and at 6 months' follow-up 5.5±5.1 and 5.4±4.2 respectively. There was no statistically significant trend for alterations of the anxiety/depression levels before and after surgery. Female patients, those suspected to have glioblastoma and patients presenting with speech disturbance had remarkably higher preoperative anxiety levels. Three patients had PTSD symptoms 3 months after AC while at 6 months there was no indication of PTSD. The decremental trend of PTSD score within 6 months was statistically significant. Conclusions Judicious application of AC is not associated with an escalation of the anxiety/depression level among the patients. Even patients with high preoperative anxiety levels could be managed with AC without severe psychological deterioration. |
| Databáze: | OpenAIRE |
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